Results 61 to 70 of about 682,769 (306)

Financial technology impact on stability of financial institutions

open access: yesTechnological and Economic Development of Economy, 2022
It is a controversial question whether financial technology makes financial institutions vulnerable (instable). This research is based on the analysis of financial institutions from 37 countries.
Jelena Stankevičienė, Jelena Kabulova
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Estimating the optimal capital adequacy level for Ukrainian banking sector

open access: yesBaltic Journal of Economics
This study presents estimates of the aggregate theoretically optimal capital adequacy level for the Ukrainian banking sector, calculated using a cost–benefit approach, which implies measuring the net effect of higher capital levels on the economy.
Yuliya Bazhenova
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Predictive Power of the User Cost Spread for Economic Recession in China and the US

open access: yesInternational Journal of Financial Studies, 2019
The predictive power of the yield curve slope, or the yield spread is well established in the United States (US) and European Union (EU) countries since 1998.
Dongfeng Chang   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Financial Stability Report 2020 : vulnerabilities and risks

open access: yes, 2020
The annual Financial Stability Report communicates Norges Bank assessments of the financial stability outlook. The Report discusses cyclical and structural developments at banks and other financial institutions and in financial markets and the Norwegian ...

core  

Financial Stability Report 2019 : vulnerabilities and Risks [PDF]

open access: yes, 2019
In the annual Financial Stability Report, Norges Bank assesses vulnerabilities and risks in the financial system, with a focus on the long-term, structural features of banks, financial markets and the Norwegian economy that are of importance for ...

core  

Home - About - Disclaimer - Privacy