Results 101 to 110 of about 1,287,133 (312)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Financial autonomy of facilities providing primary care services in low- and middle-income countries: assessing the evidence to inform the development of a typology and conceptual framework

BMC Health Services Research
Background Provider autonomy is increasingly asserted as an important attribute in health systems, but is rarely interrogated in-depth, particularly at primary care level.
Sophie Witter, Maria Paola Bertone, Lucas Sempé, Quentin Baglione, Hélène Barroy, Justine Hsu, Inke Mathauer   +6 more
doaj   +1 more source

Customer Due Diligence and Its Role To Prevent The Global Economic Threat: Indonesian Anti Money Laundering Perspectives [PDF]

, 2012
Money laundering and financing of terrorism is one of the global threats which may occur problems for the economics of the world. The effect of Money Laundering and financing of terrorism have been manifested in the life of the nations.
Lisanawati, Go
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Financing Cities [PDF]

The macro-economic and micro-economic evidences makes a persuasive case for cities as important centers for productive efficiency, innnovation, and economic growth.
Robert Inman
core  

Regional railway transport funding in conditions of the Czech Republic and in the Pilsen region [PDF]

, 2010
Present situation in financing of regional railway transport does not allow sustainable development of transport services in a region and also often leads to further worsening of situation in rolling stock financing.
Benediktová, Marcela, Chlaň, Alexander
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Financing Matters [PDF]

Farms systems are open to financial systems. Financing matters. Analysis of questions about management of farms is a multi-dimensional task; focusing on economic efficiency only partly does the job.
Malcolm, Bill
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Implementation challenges for achieving universal health coverage through social health protection scheme: what can we learn from Bangladesh?

International Journal of Qualitative Studies on Health & Well-Being
Background In Bangladesh, households experience high out-of-pocket healthcare expenditure, with below-poverty-line population being disproportionately affected.
Mohammad Wahid Ahmed, Quazi Nazmus Sakib, Md. Zahid Hasan, Gazi Golam Mehdi, Jahangir A.M. Khan, Ziaul Islam, Sayem Ahmed   +6 more
doaj   +1 more source