Results 121 to 130 of about 546,962 (306)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Financing surgery in LMICs: building sustainable and equitable systems for universal surgical access – a narrative review

open access: yesBMC Surgery
Introduction Surgical conditions account for nearly a third of the global disease burden yet financing for surgery in Low- and Middle-Income Countries (LMICs) remains fragmented, under-prioritized, and heavily dependent on out-of-pocket (OOP) payments ...
Chernet T. Mengistie   +7 more
doaj   +1 more source

The high-yield segment of the corporate bond market: a diffusion modelling approach for the United States, the United Kingdom and the euro area [PDF]

open access: yes
This study empirically examines the development of the high-yield segment of the corporate bond market in the United States, as a pioneer country, and the United Kingdom and the euro area, as later adopting countries.
de Bondt, Gabe, Marqués-Ibáñez, David
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

اسلامی ہاؤس فنانسنگ کے مروجہ طریقے اورمشکلات کا جائزہ- پاکستان کے تناظر میں [PDF]

open access: yesHazara Islamicus, 2015
The house financing products are an important part of Islamic finance. The purpose of this research is to examine the existing house financing models which are commonly practiced in Islamic financial institutions around the world.
Muhammad Asghar Shahzad
doaj  

Inventory and the Stock Market [PDF]

open access: yes
About inventory models, a concern is 'often made [that] any resemblances between the models constructed and reality are purely coincidental.' One set of factors not usually considered in textbook models of inventory decisions is suggested by well ...
Richard Kum-yew Lai
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Constraints to achieving the MDGs through domestic resource mobilization [PDF]

open access: yes
The present paper focuses on the role of domestic resource mobilization for financing poverty reduction strategies. Policy makers should be aware of important macroeconomic trade-offs associated with MDG strategies financed from tax increases or domestic
Keiji Inoue, Marco V Sanchez, Rob Vos
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An Analysis of Financing Innovation and Commercialization in Canada's Functional Food and Nutraceutical Sector [PDF]

open access: yes
Growing consumer interest in functional foods and nutraceuticals has been seen as a significant business opportunity for the agri-food sector. Many of the new firms in this sector are small and medium sized enterprises (SMEs).
Cranfield, John A.L.   +3 more
core   +1 more source

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