Results 131 to 140 of about 546,962 (306)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Sustainability of BMT financing for Developing Micro-enterprises [PDF]

open access: yes
The aim of this study is to analyze the sustainability of Islamic micro-financing for developing micro-enterprises (ME). We use the sample of Baitul Mal Wat Tamwil (BMT), as Islamic microfinance institution in Indonesia.
Ismail, Abdul Ghafar   +1 more
core   +1 more source

Promoting Consumer Choice and Innovative Financing Models: Lessons Learned From 25 Years of Supporting Long-Term Care [PDF]

open access: yes, 2007
Provides an overview of the foundation's efforts to explore new approaches to long-term care and develop and models for reform.

core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Pricing and Financing Strategies in a Dual-Channel Low-Carbon Supply Chain for Bilateral Capital-Constrained Retailers

open access: yesInternational Journal of Computational Intelligence Systems
In the context of low-carbon economy, financial constraints are prevalent among both upstream and downstream enterprises, exacerbated by the trend of online retailers extending into offline physical stores.
Limin Du, Yuhao Zhang, Keping Lu
doaj   +1 more source

Towards sustainable financing models for television production? Challenges for audiovisual policy support in small media markets [PDF]

open access: yes, 2015
This paper sets out from a contextual perspective to describe and evaluate the mix or ‘policy toolkits’ available for policymakers to sustain the financing of tv drama production in small countries, and the mechanisms to support a viable television ...
Evens, Tom   +2 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The Birth of German Biotechnology Industry: Did Venture Capital run the Show? [PDF]

open access: yes
The goal of this paper is to point out the role played by private equity investors (venture-capital companies and corporate investors) in the emergence of a new biotechnology industry in Germany in the second half of the 90?s.
Champenois, Claire   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Non-hierarchical signalling: two-stage financing game [PDF]

open access: yes
The literature analyzing games where some players have private information about their "types" is usually based on the duality of "good" and "bad" types (GB approach), where "good" type denotes the type with better quality.
Miglo, Anton, Zenkevich, Nikolay
core   +1 more source

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