Results 51 to 60 of about 83,445 (291)

Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis

Advanced Science, EarlyView.
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei, Diwen Shou, Siyuan Huang, Yingsi Wang, Quanzhen Liu, Jinfa Liu, Xiaoyu Lv, Yuyi Zeng, Liting Wei, Han Lin, Jiechuan Chen, Yangxiao Chen, Haoyu Zhong, Yanqing Zhou, Wen Ma, Li Wang, Guojun Qian, Jing Guo, Donglin Sun   +18 more
wiley   +1 more source

Fine-Needle Aspiration of Subcentimeter Thyroid Nodules in the Real-World Management

Cancer Management and Research, 2020
Chaiho Jeong,1 Hyunsam Kim,1 Jeongmin Lee,2 Jeonghoon Ha,1 Min-Hee Kim,2 Moo Il Kang,1 Dong-Jun Lim1 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University
Jeong C, Kim H, Lee J, Ha J, Kim MH, Kang MI, Lim DJ   +6 more
doaj  

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

Advanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou, Yongjian Su, Haoda Lu, Wencai Li, Weihua Yin, Shengnan Li, Huobiao Zhu, Kok Haur Ong, Gang Chen, Yong Jiang, Yifei Liu, Shenglei Li, Manchun Yang, Zhengyu Zhang, Xiaoyan Wang, Xiaohui Zhu, Xinmi Huo, Longjie Li, Chao Wang, Nanyan Zhang, Weijun Pan, Bin Shang, Xudan Yang, Yongqiang Zhu, Xiaolin Liu, Weimiao Yu, Xiuwu Bian, Yanqing Ding   +27 more
wiley   +1 more source

Proteomic approach used in the diagnosis of Riedel's thyroiditis: a case report

Journal of Medical Case Reports, 2012
Introduction Riedel's thyroiditis, a rare thyroid disease, can be difficult to diagnose prior to surgical removal and can be confused with malignancy both clinically and cytologically. Case presentation We report the case of a 72-year-old Caucasian woman
Iacconi Pietro, Giusti Laura, Da Valle Ylenia, Ciregia Federica, Giannaccini Gino, Torregrossa Liborio, Proietti Agnese, Donatini Gianluca, Mazzeo Salvatore, Basolo Fulvio, Lucacchini Antonio   +10 more
doaj   +1 more source

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR‐δ Signaling Pathway

Advanced Science, EarlyView.
Utilizing PDO, cell lines and cervical cancer xenograft (CDX) models, the study demonstrate both in vitro and in vivo that the metabolite of L. crispatus, erucic acid, can modulate the proliferation, migration and invasion of cervical cancer by activating the PPAR‐δ pathway.
Qianwei Zhen, Yuexuan Xu, Ying Xu, Xiao Liu, Yuting Zhang, Dan Ye, Sai Han, Shili Liu, Youzhong Zhang   +8 more
wiley   +1 more source

Autonomous Machine Learning‐Based Classification and Arrangement of Submillimeter Objects Using a Capillary Force Gripper

Advanced Intelligent Discovery, EarlyView.
This study presents an automated system integrating a capillary force gripper and machine learning‐based object detection for sorting and placing submillimeter objects. The system achieved stable and simultaneous manipulation of four object types, with an average task time of 86.0 seconds and a positioning error of 157 ± 84 µm, highlighting its ...
Satoshi Ando, Naoto Watanabe, Chihiro Sekine, Shogen Sekiguchi, Ohmi Fuchiwaki   +4 more
wiley   +1 more source

Fine-needle aspiration of the thyroid [PDF]

Cancer, 2000
Although fine-needle aspiration (FNA) of the thyroid is the key preoperative investigation of thyroid lesions, there are overlaps in the criteria for diagnosis of certain lesions, particularly important among which are those for follicular neoplasms.
Michael H. Cummings, David Boote, David N. Poller, Michael Perry, Ashraf K. Ibrahim, John J. Mikel   +5 more
openaire   +2 more sources

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, EarlyView.
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Role of fine needle aspiration cytology (FNAC) in head and neck neoplasms with histopathological correlation

National Journal of Clinical Anatomy, 2015
Background : Fine needle aspiration cytology is a simple, quick,inexpensive and minimally invasive technique used to diagnose head and neck neoplasms commonly originated from cervical lymph node, thyroid, parotid and other salivary glands.
Junu Devi, Kunja Lai Talukdar
doaj   +1 more source

Thyroid nodules cytopathology applying the Bethesda system with histopathological correlation

Saudi Journal of Medicine and Medical Sciences, 2018
Background: Fine-needle aspiration cytology remains a valuable screening tool for preoperative management of thyroid nodules. However, the rates of false-negative and false-positive diagnosis remain a challenge for pathologists. Objectives: To assess the
Hawazen A Zarif, Samirah E Ghandurah, Mohamed A Al-Garni, Sarah K Binmahfooz, Basim S Alsaywid, Mohamed B Satti   +5 more
doaj   +1 more source