Results 51 to 60 of about 1,579,062 (292)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

Role of fine needle aspiration cytology in evaluating the Breast Lumps

Gomal Journal of Medical Sciences, 2010
Background: Fine needle aspiration cytology is an evaluation tool for the breast lumps. This study was conducted to evaluate the results of fine needle aspiration cytology in comparison with open biopsy.
Samiullah, Saifur Rehman, Manzoor Ali, Ajmal Khan, Yasi Khalili, Anwar Ali, Amreek Lal   +6 more
doaj  

Obtaining grains via Fine Needle Aspiration.

, 2014
Obtaining grains via Fine Needle Aspiration.
Ahmed H. Fahal (407447), Wendy W. J. van de Sande (320135), El Sheikh Mahgoub (580290), Ed E. Zijlstra (85986), Oliverio Welsh (270819), Michael Goodfellow (543692)   +5 more
core   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]

, 2016
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
Jugheli, Levan, Mohamed Sasamalo, Chande, Hassan, Maira Bholla, Beck, Hans-Peter, Reither, Klaus, Edward Masika, Tracy R. Glass, Hans-Peter Beck, Masika, Edward, Sasamalo, Mohamed, Glass, Tracy R., Klaus Reither, Bholla, Maira, Levan Jugheli, Kapalata, Neema, Hassan Chande, Neema Kapalata, Bholla M, Reither K, Jugheli L, Glass TR, Chande H, Beck HP, Masika E, Sasamalo M, Kapalata N   +26 more
core   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

The Roles of Ultrasonography and Ultrasonography-guided Fine-needle Aspiration Cytology in the Planning of Management of Thyroid Cancers

Journal of Medical Ultrasound, 2015
Because of the widespread use of thyroid ultrasonography, many thyroid lesions, even thyroid cancers, can be detected early. For these small lesions, planning of the management of thyroid cancers, especially papillary thyroid cancers, is different from ...
Tien-Chun Chang
doaj   +1 more source

Soft Tissue

, 2018
Over the years, with advances in our understanding of soft tissue tumors, availability of an increasing number of diagnostic ancillary tests, and matured biopsy techniques with or without image guidance, needle biopsy investigation of a soft tissue ...
Qian, Xiaohua, Stanley, Donald E., Domanski, Henryk A., Åkerman, Måns, Åkerman, Måns,, Qian, Xiaohua,, Stanley, Donald E.,, Domanski, Henryk A.,, Lund University.   +8 more
core   +1 more source

Artificial Intelligence for Advanced Functional Materials: Progress and Emerging Frontiers

Advanced Intelligent Systems, EarlyView.
Artificial intelligence is transforming the discovery of functional materials by linking synthesis, characterization, simulation, and design in unified workflows. Advances in machine learning, autonomous experimentation, and foundation models are accelerating innovation across energy, electronics, and biomedicine, while revealing new frontiers for ...
Cristiano Malica, Kostya S. Novoselov, Seongmin Kim, Yousung Jung, Silvana Botti, Miguel A. L. Marques, Tigany Zarrouk, Miguel A. Caro, Sanggyu Chong, Michele Ceriotti, Marivi Fernandez‐Serra, Sara Navarro‐Rodriguez, Aakash Ashok Naik, Janine George, Ömer Hasan Omar, Victor Trinquet, Gian‐Marco Rignanese, Andrey Ustyuzhanin, Sonia Conesa‐Boj, Juan Rojo, Minh‐Tuan Dau, Simon M.‐M. Dubois, Jean‐Christophe Charlier, Jose H. Garcia, Romain Gautier, Rachid Laref, Junfeng Qiao, Giovanni Pizzi, Nicola Marzari, Camilla Coletti, Antonio Rossi, Jan‐Lucas Uslu, Chiara Zanardi, Vincenzo Palermo, Wide Hogenhout, Natalia Konchakova, Peter Klein, Tejs Vegge, Stephan Roche   +38 more
wiley   +1 more source