Results 41 to 50 of about 1,403,751 (269)
SOCIO-ECONOMIC DAMAGE FROM ROAD TRAFFIC ACCIDENTS AS A THREAT TO THE ECONOMIC SECURITY OF RUSSIA
Вестник Северо-Кавказского федерального университета, 2022 This article discusses the main problems associated with road safety in Russia and the Krasnodar region. The high mortality of the population as a result of road accidents leads to a decrease in the demographic situation in the country, poses a threat to
M. Shevkunenko
doaj
Frontiers in Public Health, 2022 Pharmacological neuroenhancement (PN) describes the use of divergent psychoactive substances to enhance mental performance (cognition) without medical need. This kind of substance abuse takes place predominantly in stressful situations.
Philipp Dominik +3 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen +5 more
wiley +1 more source
Faire amende devant la haute-justice d’Elbeuf à la fin du XVe siècle
Tabularia, 2006 This contribution concerns various examples of settlements of conflicts in the court of high justice at Elbeuf at the end of the fifteenth century.
Adrien Dubois
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Disparitas Penjatuhan Pidana Kurungan Pengganti Pidana Denda dalam Putusan Kasus Narkotika
Kanun, 2015 ABSTRAK: Disparitas pidana pengganti denda didasarkan pada adanya kebebasan hakim dalam menjatuhkan putusan, adanya ancaman pidana minimum dan maksimum pada Undang-Undang Narkotika, terjadinya perubahan terhadap undang-undang narkotika, penggunaan dasar ...
Nursiti Nursiti, Fakhrullah Fakhrullah
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source