Results 71 to 80 of about 505,818 (307)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Pengaruh Gradasi Agregat terhadap Karakteristik Beton Segar [PDF]
, 2014 The aim of this research is to know the effect of gradation natural aggregate to the characteristic of fresh concrete. Gradation of aggregate are found from composition of size granular fine and coarse aggregate.
pertiwi, N. (Nurlita)
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Construction MaterialsTo address SDG12 (ensure sustainable consumption and production patterns), and to provide technical evidence for alternative concrete constituents to traditional natural river sand, stone fine aggregate (SFA), brick fine aggregate (BFA), ladle-refined ...
Tarek Uddin Mohammed +6 more
doaj +1 more source
Hydro-abrasive resistance and mechanical properties of rubberized concrete
Građevinar, 2014 Results obtained by testing hydro-abrasive resistance and mechanical properties of concrete with rubber granules are presented in the paper. Fine river aggregate is replaced with 10, 20, and 30 percent of recycled granulated rubber (with respect to the ...
Zoran Grdić +4 more
doaj +1 more source
A Study Focus on Concrete Replacing LD Slag as Fine Aggregate [PDF]
, 2016 Concrete is a composite material composed of fine and coarse granular aggregate (which acts as a filler material) embedded in a hard matrix of cement (which acts as binder) that fills the space among the aggregate particles and glue them together.
Behre, S. (Shemilis) +4 more
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Potential Applicability of Air-Cooled Ladle Furnace Slag Fine Aggregate in Concrete Production
RecyclingElectric arc furnace oxidizing slag (EAFOS) represents 80% of the electric arc furnace slag generated. Recently, EAFOS has been utilized as high value-added functional aggregate in a growing number of cases for the construction of air-cooling technology ...
Jeongmin Ra +3 more
doaj +1 more source
Crack Initiation Assessment of Wearing Course Asphalt Mixtures Using Aggregate Gradation Characteristic [PDF]
, 2007 At normal service temperatures, wearing course asphalt mixtures may have ductile cracking. Aggregate gradation characteristic is important to avoid the premature cracking. The present study discusses a relationship between the characteristic of aggregate
Haryanto, I. (Iman), Takahashi, O. (O)
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source