Results 81 to 90 of about 4,152,355 (273)

Improving Fine Motor and Handwriting Skills [PDF]

Early childhood years are a crucial time for the development of fine motor and handwriting skills. Research links these skills to success in other academic content such as letter identification and counting skills.
Weber, Anne
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The association between gross motor skills, fine motor skills and early mathematical skills in 4-years-old children [PDF]

, 2022
Tavoitteet. Tämän tutkielman tarkoituksena oli selvittää, miten 4-vuotiaiden lasten heikot karkeamotoriset taidot ovat yhteydessä heidän hienomotorisiin ja varhaisiin matemaattisiin taitoihinsa.
Mattila, Venla
core  

Promotion of Fine Motor Skills Through Video Supports [PDF]

, 2021
Pediatric occupational therapists working with students in a school-based setting are consistently facing challenges with time management due to their high caseload numbers and limited documentation time in school-based settings.
Hasher, Kaitlin
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

FINE MOTOR SKILLS IN PRESCHOOL CHILDREN

, 2021
Fina motorika predstavlja dio motoričkog razvoja kroz koje dijete prolazi. Dijete od pete godine počinje intenzivnije raditi na finoj motorici te intenzivniji razvoj traje do desete godine njegova života.
Šutalo, Mislav
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Motor skills in kindergarten: Internal structure, cognitive correlates and relationships to background variables [PDF]

, 2017
The present study aimed to contribute to the discussion about the relation between motor coordination and executive functions in preschool children. Specifically, the relation between gross and fine motor skills and executive functions as well as the ...
Venera Gashaj, Oberer, Nicole, Gashaj, Venera, Claudia M. Roebers, Roebers, Claudia M., Nicole Oberer   +5 more
core   +3 more sources