Results 91 to 100 of about 520,472 (308)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Charging the Poor: Criminal Justice Debt & Modern-Day Debtors’ Prisons [PDF]

open access: yes, 2016
Debtors’ prisons should no longer exist. While imprisonment for debt was common in colonial times in the United States, subsequent constitutional provisions, legislation, and court rulings all called for the abolition of incarcerating individuals to ...
Sobol, Neil L.
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Effect of Fines Content on the Compression Behavior of Calcareous Sand

open access: yesApplied Sciences
Due to the hydraulic sorting effect in the hydraulic filling process, a fine-grained aggregate layer dominated by silty fine sand with uneven distribution is easily formed in reclamation projects, which triggers issues with the bearing capacity and ...
Suhang Huang, Xiaonan Gong
doaj   +1 more source

Laboratory study on the effects of hydraulic and granulometric parameters on the response of granular soil to internal erosion [PDF]

open access: yes, 2019
Erosion is a major environmental problem to agricultural land as well as to civil engineering infrastructures. Rainwater infiltration into granular soils can lead to the migration of fine particles by suffusion.
BENDANI, Karim   +2 more
core  

"DEVELOPMENT OF WOOD GRINDING 5. FINES CONTENT–TO–SHIVES RATIO "

open access: yesCellulose Chemistry and Technology, 2022
"Data by Riissanen were largely applied to learn more about wood grinding and, particularly, possible effects of the moisture content in spruce wood, varying from 65 to 15%, which in terms of moisture ratio covers a range from 1.9 to 0.2 kg water per kg oven dry wood.
openaire   +1 more source

Mechanical properties of coarse-fine particle mixtures: a laboratory investigation of the effect of fine content

open access: yes, 2023
Abstract The impacts of fine content on the microstructure and mechanical behavior of five types of coarse-fine particle mixtures with different fine contents are examined based on laboratory tests. The samples used in these tests all had a void ratio of 0.6.
Liucheng Chang, Ya Wang, Hongyu Wang
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

A New Shear Wave Velocity-Based Liquefaction Probability Model Using Logistic Regression: Emphasizing Fines Content Optimization

open access: yesApplied Sciences
A new liquefaction probability model based on shear wave velocity (Vs) was developed through a detailed comparative analysis of existing evaluation methods.
Yang Yang, Yitong Wei
doaj   +1 more source

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