Results 41 to 50 of about 8,734 (263)
Geologia Croatica, 2011 This laboratory investigation has been conducted to elucidate how the fines fraction affects the undrained residual shear strength and liquefaction potential of sand-silt mixtures (Algeria).
Mostefa Belkhatir +4 more
doaj +1 more source
New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation. [PDF]
PLoS ONE, 2014 Fine excipient particles or 'fines' have been shown to improve the dispersion performance of carrier-based formulations for dry powder inhalation. Mechanistic formulation studies have focussed mainly on explaining this positive effect.
Floris Grasmeijer +6 more
doaj +1 more source
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FALL CONE TEST CALIBRATION FOR SLOPE STABILITY ANALYSIS
Rudarsko-geološko-naftni ZbornikUndrained shear strength is considered as an essential factor to assess the stability of natural slopes and embankments. Traditionally, this parameter is determined through laboratory tests, which are often costly and time-consuming.
Chalabi Youssouf +3 more
doaj +1 more source
Particle-scale insight into transitional behaviour of gap-graded materials – small-strain stiffness and frequency response [PDF]
E3S Web of Conferences, 2019 This study aims to develop a fundamental understanding of the role of fine particles on the small-strain stiffness of gap-graded granular soils. Stiffness was measured using cyclic triaxial probes, which give a measure of static stiffness, and dynamic ...
Otsubo Masahide +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source