Results 51 to 60 of about 520,472 (308)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Particle-scale insight into transitional behaviour of gap-graded materials – small-strain stiffness and frequency response [PDF]
E3S Web of Conferences, 2019 This study aims to develop a fundamental understanding of the role of fine particles on the small-strain stiffness of gap-graded granular soils. Stiffness was measured using cyclic triaxial probes, which give a measure of static stiffness, and dynamic ...
Otsubo Masahide +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Studi Karakteristik Pasir Siuri dengan Penambahan Butiran Halus Nonplastis (Studi Kasus Fc [PDF]
, 2013 Physical and mechanical properties of uniform sand (Siuri sand) mixed with fine grains is not the same as pure uniform sand, and the void ratio (e) can not be considered as appropriate index to describe the microstructure changes due to the fine grains ...
Chandra, H. (Herfiya) +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Evaluation of salmon and steelhead spawning habitat quality in the South Fork Trinity River Basin, 1997 [PDF]
, 1997 Sediment sampling was used to evaluate chinook salmon (Oncorhynchus tshawytscha) and steelhead (O. mykiss) spawning habitat quality in the South Fork Trinity River (SFTR) basin.
Borok, Sara L., Jong, Howard W.
core
Sedimentological and scanning electron microscopic descriptions of Afowo oil sand deposits, Southwestern Nigeria. [PDF]
, 2017 Sedimentological and scanning electron microscopic analyses of some shallow reservoir tar sand samples in parts of Southwestern Nigeria were carried out with the aim of characterizing the reservoir properties in relation to bitumen saturation and ...
Akinmosin, Adewale, Melifonwu, Chioma V.
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source