Results 41 to 50 of about 108,580 (297)

Initial results of finger imaging using Photoacoustic Computed Tomography [PDF]

open access: yes, 2014
We present a photoacoustic computed tomography investigation on a healthy human finger, to image blood vessels with a focus on vascularity across the interphalangeal joints.
Biswas, Samir K.   +4 more
core   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Gyroscope Sensor Based In Vivo Finger Axes of Rotation Identification Using Screw Displacement

open access: yesApplied Bionics and Biomechanics, 2021
This paper presents a low-cost, efficient, and portable in vivo method for identifying axes of rotation of the proximal interphalangeal and distal interphalangeal joints in an index finger.
Yiming Zhu   +4 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Anthropomorphic modular gripper finger actuated by antagonistic wire and shape-memory alloy (SMA) springs [PDF]

open access: yesMechanical Sciences
The traditional underactuated grippers can only passively adapt to the contour of the object, and the passive contact process may lead to the object slipping, affecting the stability of the grasping process.
L. Sun, L. Sun, Y. Lan, B. Wang
doaj   +1 more source

Case for diagnosis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Pachydermodactyly is a rare and benign form of acquired digital fibromatosis characterized by the expansion of soft tissue around proximal phalanges and interphalangeal joints.
Camila Bueno Requena   +3 more
doaj   +1 more source

Dexterous manipulation of unknown objects using virtual contact points [PDF]

open access: yes, 2019
The manipulation of unknown objects is a problem of special interest in robotics since it is not always possible to have exact models of the objects with which the robot interacts. This paper presents a simple strategy to manipulate unknown objects using
Montaño Sarria, Andrés Felipe   +1 more
core   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Fingertip force estimation method of a human-like 3DOF robotic finger capable of fast tapping motion

open access: yesNihon Kikai Gakkai ronbunshu, 2023
There are several studies focusing on rapid tapping motion for a robotic finger, including not only a theoretical approach of musculoskeletal modeling of a human finger but also an empirical challenge with robotic finger.
Takahiro INOUE   +3 more
doaj   +1 more source

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