Results 101 to 110 of about 8,525 (308)

Study of the influence of cutting parameters on tool wear and the state of the machined surface

Advances in Mechanical Engineering
This work presents a study of wear on the clearance face of turning tools. This study will contribute to the development of improved machining precision and efficiency while extending tool life and also ensuring the surface quality produced, despite wear
Benattia Bloul, Hélène Chanal, Merzouk Meziane   +2 more
doaj   +1 more source

Sustainability assessment of machining Al 6061-T6 using Taguchi-grey relation integrated approach

Heliyon
Modern machining requires reduction in energy usage, surface roughness, and burr width to produce finished or near-finished parts. To ensure high surface quality in machining processes, it is crucial to minimize surface finish and minimize burr width ...
Sajid Raza Zaidi, Shahid Ikramullah Butt, Muhammad Ali Khan, Muhammad Iftikhar Faraz, Syed Husain Imran Jaffery, Jana Petru   +5 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Investigation into the effect of fixturing systems on the design of condition monitoring for machining operations

, 2013
The global market competition has drawn the manufacturer’s attention on automated manufacturing processes using condition monitoring systems. These systems have been used for improving product quality, eliminating inspection, and enhancing manufacturing ...
Abbas, JK
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Determination of machinable volume for finish cuts in CAPP

, 2005
Identification of machinable volume for finish cut is a complex task as it involves the details not only of the final product but also the intermediate part obtained from rough machining of the blank.
Jain, PK, Arivazhagan, A, Mehta, NK
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

SURFACE FINISH WHEN THREADING TITANIUM-BASED ALLOY UNDER DRY MACHINING

, 2020
This paper discusses the quality of surface finish when threading titanium-based alloy under dry condition. The quality of surface finish was studied at various cutting parameters and at the two extreme stages of the machining process, i.e.
John Rizal Biki, Ahmad Yasir, Siti Hartini Hamdan, Md Said   +3 more
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source