Results 81 to 90 of about 65,109 (285)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

ACCOUNTING OF INSTRUMENTAL ERRORS IN THE CONTROL OF WINDINGS OF ELECTRICAL MACHINES WITH THE USE OF QUASI-PERIODIC TEST SIGNALS

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2018
The solution of problems of diagnostics of windings of electric machines is associated with the necessity of selection of quasi-periodic test signals against the background noise.
A. A. Sheinikov   +2 more
doaj   +1 more source

Finitely additive conditional probabilities [PDF]

open access: yesRendiconti del Seminario Matematico e Fisico di Milano, 1985
This paper includes a concise survey of the work done in order to extend de Finetti's coherence condition to the prevision of conditional random quantities. Sections 1 and 2 deal with the equivalence among different formulations of the extended condition and analyse the relations between it and the usual axiomatic treatment of finitely additive ...
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Geometric and homotopy theoretic methods in Nielsen coincidence theory

open access: yesFixed Point Theory and Applications, 2006
In classical fixed point and coincidence theory, the notion of Nielsen numbers has proved to be extremely fruitful. Here we extend it to pairs (f1,f2) of maps between manifolds of arbitrary dimensions.
Ulrich Koschorke
doaj   +1 more source

On asymptotic scales of independently stopped random sums [PDF]

open access: yes, 2014
We study randomly stopped sums via their asymptotic scales. First, finiteness of moments is considered. To generalise this study, asymptotic scales applicable to the class of all heavy-tailed random variables are used.
Lehtomaa, Jaakko
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Spectrum and resolvent of multi-channel systems with internal energies and common boundary conditions

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In the article the spectrum and resolvent of the so-called multichannel systems with nonzero internal energies were investigated. The spectrum and resolvent of multichannel Sturm-Liouville systems with non-zero internal energies mi2 and general boundary
A.A. Valiyev   +2 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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