Results 121 to 130 of about 41,483 (313)
Scale modeling studies on smoke control using smoke screens in a titled tunnel fire
, 2012 Many tunnels, which are inclined to the horizontal, are built in Mainland China, Hong Kong, and Taiwan. Smoke control systems are installed to minimize damage in tunnels in case of fire.
Chow, W
core +1 more source
Advanced Science, EarlyView.In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source
The Application of a Genetic Algorithm to Estimate Material Properties for Fire Modeling from Bench-Scale Fire Test Data [PDF]
, 2005 A methodology based on an automated optimization technique that uses a genetic algorithm (GA) is developed to estimate the material properties needed for CFD-based fire growth modeling from bench-scale fire test data.
Rein, Guillermo +2 more
core
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Locating fire-stations: an integrated approach for Belgium [PDF]
This paper demonstrates the potential of a decision-support system developed for Belgium by a consortium of universities and a private firm, in the framework of a public call by the Ministry of the Interior.
CHEVALIER, Philippe +3 more
core
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
BRINGING THE FIRE EFFECTS INFORMATION SYSTEM UP-TO-DATE AND IMPROVING SERVICE TO LAND MANAGERS
, 2008 This project delivers up-to-date, science-based information about species nominated by wildland managers for revision in or addition to the Fire Effects Information System (FEIS). FEIS now provides 1,081 literature reviews covering 1,139 taxa.
Fire Modeling Institute Information Team +1 more
core
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
FireThe Wan’an Bridge, the longest wooden lounge bridge in China with a history of more than 900 years, was devastated by a catastrophic fire in 2022. This tragic event underscores the susceptibility of historical wooden structures to fire damage.
Huiling Jiang +4 more
doaj +1 more source
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source