Results 1 to 10 of about 337,560 (313)
The application of convolutional neural network to stem cell biology [PDF]
Inflammation and Regeneration, 2019 Induced pluripotent stem cells (iPSC) are one the most prominent innovations of medical research in the last few decades. iPSCs can be easily generated from human somatic cells and have several potential uses in regenerative medicine, disease modeling, drug screening, and precision medicine.
Dai Kusumoto +2 more
exaly +4 more sources
Ancestral glycoprotein hormone-receptor pathway controls growth in C. elegans
Frontiers in Endocrinology, 2023 In vertebrates, thyrostimulin is a highly conserved glycoprotein hormone that, besides thyroid stimulating hormone (TSH), is a potent ligand of the TSH receptor.
Signe Kenis +6 more
doaj +1 more source
A novel retinal ganglion cell quantification tool based on deep learning
Scientific Reports, 2021 Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin +7 more
doaj +1 more source
Atp11b Deletion Affects the Gut Microbiota and Accelerates Brain Aging in Mice
Brain Sciences, 2022 The microbiota-gut-brain axis has attracted significant attention with respect to studying the mechanisms of brain aging; however, the specific connection between gut microbiota and aging remains unclear.
Cuiping Liu +7 more
doaj +1 more source
Building blocks of consciousness: Revealing the shared, hidden depths of our biological heritage
HTS Teologiese Studies/Theological Studies, 2020 Human consciousness has been a hard problem for thousands of years and, in the course of time, variously interpreted and often too narrowly defined. As a result, the possibility of animal consciousness, sentience or even the possibility that animals can ...
Juri van den Heever, Chris Jones
doaj +1 more source
MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System
Cells, 2021 Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries +11 more
doaj +1 more source
Ultrafast Image Categorization in Biology and Neural Models
Vision, 2023 Humans are able to categorize images very efficiently, in particular to detect the presence of an animal very quickly. Recently, deep learning algorithms based on convolutional neural networks (CNNs) have achieved higher than human accuracy for a wide range of visual categorization tasks.
Jean-Nicolas Jérémie +1 more
openaire +4 more sources
Reelin function in neural stem cell biology [PDF]
Proceedings of the National Academy of Sciences, 2002 In the adult brain, neural stem cells (NSC) must migrate to express their neuroplastic potential. The addition of recombinant reelin to human NSC (HNSC) cultures facilitates neuronal retraction in the neurospheroid. Because we detected reelin, α3-integrin receptor subunits, and disabled-1 immunoreactivity in HNSC cultures, it is possible that integrin ...
H M, Kim +8 more
openaire +2 more sources
Biology of the adult enteric neural stem cell [PDF]
Developmental Dynamics, 2006 AbstractAn increasing body of evidence has accumulated in recent years supporting the existence of neural stem cells in the adult gut. There are at least three groups that have obtained them using different methodologies and have described them in vitro.
Sandino, Estrada-Mondaca +2 more
openaire +2 more sources
Communications Biology, 2021 Elder et al. investigated the de novo proteome in isolated hippocampal slices of young APP/PS1 Alzheimer’s model mice and revealed that large-scale changes in protein synthesis precede symptom onset.
Megan K. Elder +5 more
doaj +1 more source