Results 1 to 10 of about 335,459 (219)
Ancestral glycoprotein hormone-receptor pathway controls growth in C. elegans
Frontiers in Endocrinology, 2023 In vertebrates, thyrostimulin is a highly conserved glycoprotein hormone that, besides thyroid stimulating hormone (TSH), is a potent ligand of the TSH receptor.
Signe Kenis +6 more
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Atp11b Deletion Affects the Gut Microbiota and Accelerates Brain Aging in Mice
Brain Sciences, 2022 The microbiota-gut-brain axis has attracted significant attention with respect to studying the mechanisms of brain aging; however, the specific connection between gut microbiota and aging remains unclear.
Cuiping Liu +7 more
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A novel retinal ganglion cell quantification tool based on deep learning
Scientific Reports, 2021 Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin +7 more
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Building blocks of consciousness: Revealing the shared, hidden depths of our biological heritage
HTS Teologiese Studies/Theological Studies, 2020 Human consciousness has been a hard problem for thousands of years and, in the course of time, variously interpreted and often too narrowly defined. As a result, the possibility of animal consciousness, sentience or even the possibility that animals can ...
Juri van den Heever, Chris Jones
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MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System
Cells, 2021 Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries +11 more
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Dcf1 induces glioblastoma cells apoptosis by blocking autophagy
Cancer Medicine, 2022 Background Dcf1 has been demonstrated to play vital roles in many CNS diseases, it also has a destructive role on cell mitochondria in glioma cells and promotes the autophagy.
Guanghong Luo +7 more
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Communications Biology, 2021 Elder et al. investigated the de novo proteome in isolated hippocampal slices of young APP/PS1 Alzheimer’s model mice and revealed that large-scale changes in protein synthesis precede symptom onset.
Megan K. Elder +5 more
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Food Science and Human Wellness, 2023 Benzo[a]pyrene (B[a]P) is a food contaminant toxic for cardiovascular diseases. The nuclear translocation of Arylhydrocarbon receptor (AhR) plays an important role in B[a]P-induced oxidative stress and vascular diseases.
Rong Wang +11 more
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Multi-Modal Pain Intensity Assessment Based on Physiological Signals: A Deep Learning Perspective
Frontiers in Physiology, 2021 Traditional pain assessment approaches ranging from self-reporting methods, to observational scales, rely on the ability of an individual to accurately assess and successfully report observed or experienced pain episodes.
Patrick Thiam +5 more
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CRYAA and GJA8 promote visual development after whisker tactile deprivation
Heliyon, 2023 Deprivation of one sense can be followed by enhanced development of other senses via cross-modal plasticity mechanisms. To study the effect of whisker tactile deprivation on vision during the early stages of development, we clipped the bilateral whiskers
Shibo Zhang +9 more
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