Results 31 to 40 of about 3,276,277 (298)
Journal of Integrative Neuroscience, 2022 The innate immune system primarily gets triggered by microbe infiltration, injury, stress, aging, and brain disorders. The hyperactivation of the innate immune system and neuroinflammatory reactions contributes to chronic age-related neurodegeneration ...
Nibedita Nayak, Monalisa Mishra
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Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
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Neural network models and deep learning - a primer for biologists [PDF]
Current Biology, 2019 Originally inspired by neurobiology, deep neural network models have become a powerful tool of machine learning and artificial intelligence. They can approximate functions and dynamics by learning from examples.
N. Kriegeskorte, Tal Golan
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Harnessing protein folding neural networks for peptide–protein docking
Nature Communications, 2021 Highly accurate protein structure predictions by deep neural networks such as AlphaFold2 and RoseTTAFold have tremendous impact on structural biology and beyond.
Tomer Tsaban +5 more
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Performance of neural network basecalling tools for Oxford Nanopore sequencing
Genome Biology, 2019 Basecalling, the computational process of translating raw electrical signal to nucleotide sequence, is of critical importance to the sequencing platforms produced by Oxford Nanopore Technologies (ONT).
R. Wick, L. Judd, K. Holt
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Can Abnormality be Detected by Graph Neural Networks?
International Joint Conference on Artificial Intelligence, 2022 Anomaly detection in graphs has attracted considerable interests in both academia and industry due to its wide applications in numerous domains ranging from finance to biology.
Ziwei Chai +6 more
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Dcf1 Deficiency Attenuates the Role of Activated Microglia During Neuroinflammation
Frontiers in Molecular Neuroscience, 2018 Microglia serve as the principal immune cells and play crucial roles in the central nervous system, responding to neuroinflammation via migration and the execution of phagocytosis. Dendritic cell-derived factor 1 (Dcf1) is known to play an important role
Jiao Wang +11 more
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The Molecular Biology of FMRP: New Insights into Fragile X Syndrome
Nature Reviews Neuroscience, 2021 Fragile X mental retardation protein (FMRP) is the product of the fragile X mental retardation 1 gene (FMR1), a gene that — when epigenetically inactivated by a triplet nucleotide repeat expansion — causes the neurodevelopmental disorder fragile X ...
J. Richter, Xinyu Zhao
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Journal of Advanced Research, 2022 Introduction: Hypoxia-inducible factor (HIF)1α has been shown to be activated and induces a glycolytic shift under hypoxic condition, however, little attention was paid to the role of HIF1α-actuated fructolysis in hypoxia-induced heart injury. Objectives:
Yu Zhang +8 more
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The Graph Neural Network Model
IEEE Transactions on Neural Networks, 2009 Many underlying relationships among data in several areas of science and engineering, e.g., computer vision, molecular chemistry, molecular biology, pattern recognition, and data mining, can be represented in terms of graphs.
F. Scarselli +4 more
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