Results 41 to 50 of about 3,276,277 (298)
Mitochondrial signalling and homeostasis: from cell biology to neurological disease.
Trends in Neurosciences, 2023 Efforts to understand how mitochondrial dysfunction contributes to neurodegeneration have primarily focussed on the role of mitochondria in neuronal energy metabolism.
J. Collier +3 more
semanticscholar +1 more source
Insights into neural stem cell biology from flies [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2007 Drosophila neuroblasts are similar to mammalian neural stem cells in their ability to self-renew and to produce many different types of neurons and glial cells. In the past two decades, great advances have been made in understanding the molecular mechanisms underlying embryonic neuroblast formation, the ...
Boris, Egger +2 more
openaire +2 more sources
Advanced Science, 2023 Epidemiological studies show an association between inflammatory bowel disease (IBD) and increased risk of thrombosis. However, how IBD influences thrombosis remains unknown. The current study shows that formation of neutrophil extracellular traps (NETs)
Long Zhang +10 more
doaj +1 more source
Physiological and pathological effects of amyloid-β species in neural stem cell biology
Neural Regeneration Research, 2019 Although amyloid-β peptide is considered neurotoxic, it may mediate several physiological processes during embryonic development and in the adult brain. The pathological function of amyloid-β peptide has been extensively studied due to its implication in
Adela Bernabeu-Zornoza +5 more
semanticscholar +1 more source
Cancer Communications, 2022 Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain tumor. Patients with GBM often have poor prognoses, with a median survival of ∼15 months.
E. Verdugo, Iker Puerto, M. Medina
semanticscholar +1 more source
Editorial: “Unravelling neural stem cell biology: players and strategies”
Frontiers in Cell and Developmental Biology, 2023 The properties and behaviour of adult or somatic neural stem cells (NSCs) are governed by a complex network of intrinsic molecules and pathways along with a milieu of extrinsic signals hailed from the extremely controlled environment or niche in which they reside.
Ma Salomé Sirerol-Piquer +9 more
openaire +6 more sources
Cancer CellNerves are integral to tumor biology, yet the peri- and intra-neural microenvironment and their roles in cancer-neural invasion (NI) remain underexplored.
Min-Min Chen +15 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
wiley +1 more source
Neural Regeneration Research, 2019 The pathological implication of amyloid precursor protein (APP) in Alzheimer’s disease has been widely documented due to its involvement in the generation of amyloid-β peptide. However, the physiological functions of APP are still poorly understood.
Raquel Coronel +6 more
semanticscholar +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source