Results 41 to 50 of about 777,664 (296)

The ASD Living Biology: from cell proliferation to clinical phenotype. [PDF]

, 2019
Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the lay public because of its uncertain origins and striking and unexplained clinical heterogeneity.
Courchesne, Eric, Gazestani, Vahid H, Lewis, Nathan E, Lombardo, Michael V, Pierce, Karen, Pramparo, Tiziano   +5 more
core  

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Stem cells and the origin of gliomas: A historical reappraisal with molecular advancements. [PDF]

, 2009
The biology of both normal and tumor development clearly possesses overlapping and parallel features. Oncogenes and tumor suppressors are relevant not only in tumor biology, but also in physiological developmental regulators of growth and differentiation.
Ho, Allen L, Hughes, Samuel, Jandial, Rahul, Levy, Michael L, Menon, Jayant   +4 more
core   +3 more sources

Gain control network conditions in early sensory coding [PDF]

, 2013
Gain control is essential for the proper function of any sensory system. However, the precise mechanisms for achieving effective gain control in the brain are unknown.
A Couto, A Destexhe, AF Silbering, AF Silbering, B Haider, Brian H. Smith, BW Strowbridge, C Buckley, CC Girardin, CI Bargmann, CJP Vicente, CM Root, Cv Vreeswijk, D Dominguez, DA McCormick, E Av-Ron, E Salinas, EA Hallem, EA Hallem, Eduardo Serrano, F Locatelli, GA Wright, GC Turner, H Belmabrouk, H Breer, HR Wilson, I Ito, IP Sudhakaran, J Huang, J Perez-Orive, JJ Hopfield, K Touhara, LF Abbott, M Bazhenov, M García-Sanchez, M Ng, M Papadopoulou, M Rabinovich, M Schmuker, M Stopfer, M Yokoi, N Yamagata, O Shriki, Olaf Sporns, P Anderson, P Szyszka, R Huerta, R Huerta, R Huerta, Rafael Levi, Ramón Huerta, RI Wilson, RI Wilson, S Das, S Grossberg, S Krofczik, S Sachse, Si Amari, SR Olsen, SR Olsen, SR Olsen, T Nowotny, TA Cleland, TA Cleland, Thomas Nowotny, TP Vogels, V Bhandawat, Y Shang   +67 more
core   +5 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cholesterol induced-mitochondrial calcium dysregulation facilitates atherosclerosis by promoting lipid accumulation in vascular smooth muscle cells

Molecular Biomedicine
Mitochondria play an essential role in regulating various physiological functions including bioenergetics, calcium homeostasis, redox signaling, and lipid metabolism and also are involved in the pathogenesis of cardiovascular diseases.
Zhiwang Zhang, Fan Yang, Wei Wang, Qi Cao, Long Zhang, Yu Zhang, Dong Ma, Xinhua Zhang, Jinkun Wen, Bin Zheng   +9 more
doaj   +1 more source

Mendelian randomization studies of diagnostic value of standard biochemistry serum enzymes portfolio in cardiovascular diseases

Archives of Medical Science
Introduction Material and methods Results ...
Jiajing Liu, Qi Cao, Daiyao Lu, Bin Zheng, Jinkun Wen   +4 more
doaj   +1 more source

Nanoparticles used in dentistry: A review

Journal of Oral Biology and Craniofacial Research, 2018
Nanotechnology is widely used in our day to day life including its use in medicine. Using nanotechnology, it is easy to analyze and manipulate atoms, chemical bonds and molecules present between various compounds.
Subhashree Priyadarsini, Sumit Mukherjee, Monalisa Mishra   +2 more
doaj   +1 more source

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells

Communications Biology, 2022
KLF4-induced phenotypic switching of vascular smooth muscle cells occurs in atherosclerosis. Now, KLF4 is shown to induce a glycolytic shift involving upregulation of PFKFB3 expression through circular RNA CTDP1 and eukaryotic elongation factor eEF1A2.
Xinhua Zhang, Bin Zheng, Lingdan Zhao, Jiayi Shen, Zhan Yang, Yu Zhang, Ruirui Fan, Manli Zhang, Dong Ma, Lemin Zheng, Mingming Zhao, Huirong Liu, Jinkun Wen   +12 more
doaj   +1 more source

Comprehensive transcript-level analysis reveals transcriptional reprogramming during the progression of Alzheimer’s disease

Frontiers in Aging Neuroscience, 2023
BackgroundAlzheimer’s disease (AD) is a common neurodegenerative disorder that has a multi-step disease progression. Differences between moderate and advanced stages of AD have not yet been fully characterized.Materials and methodsHerein, we performed a ...
Hao Wu, Jiao Wang, Xiaoyuan Hu, Cheng Zhuang, Jianxin Zhou, Peiru Wu, Shengli Li, Robert Chunhua Zhao, Robert Chunhua Zhao   +8 more
doaj   +1 more source