Results 61 to 70 of about 335,509 (265)
Chemical and Biological Technologies in AgricultureExploring indoleacetic acid (IAA) biosynthesis pathways of plant growth promoting bacteria and their ability to synthesize IAA is crucial for understanding the promotion mechanism and for developing more efficient microbial fertilizer. In this study, 118
Yanhui Feng +8 more
doaj +1 more source
Representation of multiple objects in macaque category-selective areas
Nature Communications, 2018 Inferotemporal cortex (IT) neurons respond to specific objects but the precise neural mechanisms for clutter-invariant representation is not known. Here the authors show that face and body patch IT neurons respond to multiple objects with winner-take-all,
Pinglei Bao, Doris Y. Tsao
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Altered steady state and activity-dependent de novo protein expression in fragile X syndrome
Nature Communications, 2019 Elevated protein synthesis, and dysregulated mGluR signalling, are documented in fragile X syndrome (FXS) Here the authors use proteomic analysis in a mouse model of FXS, and following mGluR5 stimulation, to identify potential biomarkers for the disease.
Heather Bowling +16 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Show a Threshold Effect in Response to Radiation
Dose-Response, 2014 We investigate the biological effects of radiation using adult Drosophila melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses.
Michael Antosh +5 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2017 Aging progression is a process that an individual encounters as they become older, and usually results from a series of normal physiological changes over time.
Jiao Wang +10 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation
Communications BiologyAberrant autophagy in vascular smooth muscle cells (VSMCs) is associated with the progression of vascular remodeling diseases caused by neointimal hyperplasia.
Shi-Qing Mu +16 more
doaj +1 more source
Cell Transplantation, 2016 Stem cell transplantation has enormous potential for the treatment of neurodegenerative disorders like Parkinson's disease (PD). Mesenchymal stem cells (MSCs) have attracted much attention because they can secrete a wide variety of cellular factors that ...
Yuan Yao +3 more
doaj +1 more source