Results 51 to 60 of about 3,276,277 (298)

Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System

open access: yesMediators of Inflammation, 2017
Damage to the central nervous system (CNS) is one of the leading causes of morbidity and mortality in elderly, as repair after lesions or neurodegenerative disease usually fails because of the limited capacity of CNS regeneration.
Ilse Bollaerts   +4 more
doaj   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

Cholesterol induced-mitochondrial calcium dysregulation facilitates atherosclerosis by promoting lipid accumulation in vascular smooth muscle cells

open access: yesMolecular Biomedicine
Mitochondria play an essential role in regulating various physiological functions including bioenergetics, calcium homeostasis, redox signaling, and lipid metabolism and also are involved in the pathogenesis of cardiovascular diseases.
Zhiwang Zhang   +9 more
doaj   +1 more source

Mendelian randomization studies of diagnostic value of standard biochemistry serum enzymes portfolio in cardiovascular diseases

open access: yesArchives of Medical Science
Introduction Material and methods Results ...
Jiajing Liu   +4 more
doaj   +1 more source

17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Intimal hyperplasia is a major complication of restenosis after angioplasty. The abnormal proliferation and oxidative stress of vascular smooth muscle cells (VSMCs) are the basic pathological feature of neointimal hyperplasia.
Dan-dan Feng   +10 more
doaj   +1 more source

Progenitor Cell Biology [PDF]

open access: yesArchives of Neurology, 1999
A few brief years ago, damage to the central nervous system was generally perceived to be irreparable, and loss of neurons was largely viewed as an irreversible process. However, major advances in the study of neural progenitor cells have altered these perceptions, and rational approaches to the repair of the damaged nervous system using transplanted ...
M F, Mehler, J A, Kessler
openaire   +2 more sources

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

Nanoparticles used in dentistry: A review

open access: yesJournal of Oral Biology and Craniofacial Research, 2018
Nanotechnology is widely used in our day to day life including its use in medicine. Using nanotechnology, it is easy to analyze and manipulate atoms, chemical bonds and molecules present between various compounds.
Subhashree Priyadarsini   +2 more
doaj   +1 more source

Emergent Properties of Neural Repair: Elemental Biology to Therapeutic Concepts

open access: yesAnnals of Neurology, 2016
Stroke is the leading cause of adult disability. The past decade has seen advances in basic science research of neural repair in stroke. The brain forms new connections after stroke, which have a causal role in recovery of function.
S. Carmichael
semanticscholar   +1 more source

Transplanting neural progenitor cells to restore connectivity after spinal cord injury

open access: yesNature Reviews Neuroscience, 2020
Spinal cord injury remains a scientific and therapeutic challenge with great cost to individuals and society. The goal of research in this field is to find a means of restoring lost function.
I. Fischer, J. Dulin, Michael Aron Lane
semanticscholar   +1 more source

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