Results 21 to 30 of about 337,560 (313)
The representation of colored objects in macaque color patches
Nature Communications, 2017 Neurons in the inferotemporal cortex (IT) encode object identity; however, how object color is represented here is not well understood. Here the authors report that neurons from three color patches in macaque IT encode significant information regarding ...
Le Chang, Pinglei Bao, Doris Y. Tsao
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Drosophila Neural Stem Cells in Brain Development and Tumor Formation [PDF]
, 2014 Neuroblasts, the neural stem cells in Drosophila, generate the complex neural structure of the central nervous system. Significant progress has been made in understanding the mechanisms regulating the self-renewal, proliferation, and differentiation in ...
Reichert, Heinrich, Jiang, Yanrui
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Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
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Dcf1 Deficiency Attenuates the Role of Activated Microglia During Neuroinflammation
Frontiers in Molecular Neuroscience, 2018 Microglia serve as the principal immune cells and play crucial roles in the central nervous system, responding to neuroinflammation via migration and the execution of phagocytosis. Dendritic cell-derived factor 1 (Dcf1) is known to play an important role
Jiao Wang +11 more
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Journal of Advanced Research, 2022 Introduction: Hypoxia-inducible factor (HIF)1α has been shown to be activated and induces a glycolytic shift under hypoxic condition, however, little attention was paid to the role of HIF1α-actuated fructolysis in hypoxia-induced heart injury. Objectives:
Yu Zhang +8 more
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Reliable interpretability of biology-inspired deep neural networks
npj Systems Biology and Applications, 2023 Abstract Deep neural networks display impressive performance but suffer from limited interpretability. Biology-inspired deep learning, where the architecture of the computational graph is based on biological knowledge, enables unique interpretability where real-world concepts are encoded in hidden nodes, which can be ranked by ...
Wolfgang Esser-Skala, Nikolaus Fortelny
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Targeted transgenic RNAi knockdown of cell fate determinants induces neoplastic tumor growth and metastasis in a Drosophila transplantation model of neural stem cell derived cancer [PDF]
, 2012 Genetic models such as Drosophila have sophisticated transgenic and molecular genetic tools available to investigate proliferation control in normal and tumorigenic neural stem cells.
Reichert, Heinrich +3 more
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Insights into neural stem cell biology from flies [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2007 Drosophilaneuroblasts are similar to mammalian neural stem cells in their ability to self-renew and to produce many different types of neurons and glial cells. In the past two decades, great advances have been made in understanding the molecular mechanisms underlying embryonic neuroblast formation, the establishment of cell polarity and the temporal ...
Boris, Egger +2 more
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On stability and model order reduction of perturbed nonlinear neural networks [PDF]
, 2008 In this paper, the qualitative theory of large-scale dynamical systems is surveyed. In particular, the focus is the Hopfield Neural networks both with and without perturbations.
G. G. Grahovski +3 more
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VARIABILITY IN SENSORY ECOLOGY: EXPANDING THE BRIDGE BETWEEN PHYSIOLOGY AND EVOLUTIONARY BIOLOGY
, 2009 International audienceSensory organs represent the interface between the central nervous system of organisms and the environment in which they live.
Irschick, Duncan +11 more
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