Results 21 to 30 of about 777,664 (296)
The Neural Crest Migrating into the Twenty-First Century [PDF]
, 2016 From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douarin and colleagues in the latter part of the twentieth century, understanding of the neural crest has moved from the descriptive to the experimental.
Abercrombie +73 more
core +1 more source
The representation of colored objects in macaque color patches
Nature Communications, 2017 Neurons in the inferotemporal cortex (IT) encode object identity; however, how object color is represented here is not well understood. Here the authors report that neurons from three color patches in macaque IT encode significant information regarding ...
Le Chang, Pinglei Bao, Doris Y. Tsao
doaj +1 more source
Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
doaj +1 more source
Dissecting the Biological Motherboard (Systems Biology and Beyond) [PDF]
, 2008 Genome-scale molecular networks, including gene pathways, gene regulatory networks and protein interactions, are central to the investigation of the nascent disciplines of systems biology and bio-complexity.
Abhay Krishna, Ajit Narayanan
core +2 more sources
Dcf1 Deficiency Attenuates the Role of Activated Microglia During Neuroinflammation
Frontiers in Molecular Neuroscience, 2018 Microglia serve as the principal immune cells and play crucial roles in the central nervous system, responding to neuroinflammation via migration and the execution of phagocytosis. Dendritic cell-derived factor 1 (Dcf1) is known to play an important role
Jiao Wang +11 more
doaj +1 more source
Revealing networks from dynamics: an introduction [PDF]
, 2014 What can we learn from the collective dynamics of a complex network about its interaction topology? Taking the perspective from nonlinear dynamics, we briefly review recent progress on how to infer structural connectivity (direct interactions) from ...
Casadiego, Jose, Timme, Marc
core +1 more source
Journal of Advanced Research, 2022 Introduction: Hypoxia-inducible factor (HIF)1α has been shown to be activated and induces a glycolytic shift under hypoxic condition, however, little attention was paid to the role of HIF1α-actuated fructolysis in hypoxia-induced heart injury. Objectives:
Yu Zhang +8 more
doaj +1 more source
, 2023 The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce systems-biology informed neural networks for parameter estimation by incorporating the system of ODEs into the neural networks.
Daneker, Mitchell +3 more
openaire +3 more sources
The Hopfield model and its role in the development of synthetic biology [PDF]
, 2007 Neural network models make extensive use of concepts coming from physics and engineering. How do scientists justify the use of these concepts in the representation of biological systems?
Loettgers, Andrea
core +1 more source
Training deep neural density estimators to identify mechanistic models of neural dynamics [PDF]
, 2020 Mechanistic modeling in neuroscience aims to explain observed phenomena in terms of underlying causes. However, determining which model parameters agree with complex and stochastic neural data presents a significant challenge.
Bassetto, G. +11 more
core +2 more sources