Results 11 to 20 of about 335,509 (265)
Biology of the adult enteric neural stem cell [PDF]
Developmental Dynamics, 2006 AbstractAn increasing body of evidence has accumulated in recent years supporting the existence of neural stem cells in the adult gut. There are at least three groups that have obtained them using different methodologies and have described them in vitro.
Sandino, Estrada-Mondaca +2 more
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Reelin function in neural stem cell biology [PDF]
Proceedings of the National Academy of Sciences, 2002 In the adult brain, neural stem cells (NSC) must migrate to express their neuroplastic potential. The addition of recombinant reelin to human NSC (HNSC) cultures facilitates neuronal retraction in the neurospheroid. Because we detected reelin, α3-integrin receptor subunits, and disabled-1 immunoreactivity in HNSC cultures, it is possible that integrin ...
H M, Kim +8 more
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Ultrafast Image Categorization in Biology and Neural Models
Vision, 2023 Humans are able to categorize images very efficiently, in particular to detect the presence of an animal very quickly. Recently, deep learning algorithms based on convolutional neural networks (CNNs) have achieved higher than human accuracy for a wide range of visual categorization tasks.
Jean-Nicolas Jérémie +1 more
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Insights into the Biology and Therapeutic Applications of Neural Stem Cells [PDF]
Stem Cells International, 2016 The cerebral cortex is essential for our higher cognitive functions and emotional reasoning. Arguably, this brain structure is the distinguishing feature of our species, and yet our remarkable cognitive capacity has seemingly come at a cost to the regenerative capacity of the human brain.
Harris, L. +3 more
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The epitranscriptome in stem cell biology and neural development
Neurobiology of Disease, 2020 The blossoming field of epitranscriptomics has recently garnered attention across many fields by findings that chemical modifications on RNA have immense biological consequences. Methylation of nucleotides in RNA, including N6-methyladenosine (m6A), 2-O-dimethyladenosine (m6Am), N1-methyladenosine (m1A), 5-methylcytosine (m5C), and isomerization of ...
Caroline Vissers +3 more
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The representation of colored objects in macaque color patches
Nature Communications, 2017 Neurons in the inferotemporal cortex (IT) encode object identity; however, how object color is represented here is not well understood. Here the authors report that neurons from three color patches in macaque IT encode significant information regarding ...
Le Chang, Pinglei Bao, Doris Y. Tsao
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Journal of Integrative Neuroscience, 2022 The innate immune system primarily gets triggered by microbe infiltration, injury, stress, aging, and brain disorders. The hyperactivation of the innate immune system and neuroinflammatory reactions contributes to chronic age-related neurodegeneration ...
Nibedita Nayak, Monalisa Mishra
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Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
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Reliable interpretability of biology-inspired deep neural networks
npj Systems Biology and Applications, 2023 Abstract Deep neural networks display impressive performance but suffer from limited interpretability. Biology-inspired deep learning, where the architecture of the computational graph is based on biological knowledge, enables unique interpretability where real-world concepts are encoded in hidden nodes, which can be ranked by ...
Wolfgang Esser-Skala, Nikolaus Fortelny
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Dcf1 Deficiency Attenuates the Role of Activated Microglia During Neuroinflammation
Frontiers in Molecular Neuroscience, 2018 Microglia serve as the principal immune cells and play crucial roles in the central nervous system, responding to neuroinflammation via migration and the execution of phagocytosis. Dendritic cell-derived factor 1 (Dcf1) is known to play an important role
Jiao Wang +11 more
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