Results 51 to 60 of about 92,030 (297)
Advanced Science, EarlyView.Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji +13 more
wiley +1 more source
Thermal empirical equations for post-flashover compartment fires [PDF]
, 2011 10th International Symposium on Fire Safety Science, College Park, MD, 19-24 June 2011Many useful correlation equations derived for estimating the heat release rate are believed to be adequate in fire engineering application.
Wu, M, W. Chow, Chow, WK, M. Wu
core +1 more source
m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
Advanced Science, EarlyView.This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang +26 more
wiley +1 more source
Advanced Science, EarlyView.This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
FIRE DESIGN IN SAFETY ENGINEERING: LIKELY FIRE CURVE FOR PEOPLE’S SAFETY [PDF]
WIT Transactions on The Built Environment, 2017 The present study analyses fire design settings according to Fire Safety Engineering (FSE) for the simulation of fire in civil activities and compares these simulations developed using natural and analytic fire curves. The simulated Heat Rate Release (HRR) curve, appropriately linearized, allows for the estimation of a Likely Fire Curve (LFC).
LOMBARDI, MARA +4 more
openaire +2 more sources
Advanced Science, EarlyView.This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina +6 more
wiley +1 more source
Personalized Network‐Guided Neuromodulation Enhances Human Working Memory
Advanced Science, EarlyView.A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan +13 more
wiley +1 more source
Fireproof suspended ceilings with high fire resistance limits
Инженерно-строительный журнал, 2018 Suspended ceiling is an effective way to fire protection of horizontal structures with steel beams due to its lightness, reliability and functionality. Three designs of fireproof suspended ceiling with silicate plates on cement binder are considered.
Marina Gravit +3 more
doaj +1 more source