Results 221 to 230 of about 104,905 (268)

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Comparative evaluation of TRIDs : a strategy to improve treatments. [PDF]

J Transl Med
Hariss F, Spelier S, Damy L, Pacheco CS, Houpe L, Leroy C, Thuru X, Becq F, Lejeune F.   +8 more
europepmc   +1 more source

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang, Amin Javidanbardan, Ali Behboudi, Andrew L. Zydney   +3 more
wiley   +1 more source

Preliminary Investigation into the Predation of <i>Pomacea canaliculata</i> by <i>Aquatica leii</i> Larvae. [PDF]

Insects
Luo J, An C, Wu Y, Xu H.
europepmc   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Computational machine learning analysis and validation for estimation of viscosity of ionic liquids versus temperature and composition. [PDF]

Front Chem
Liu Y, Chen H, Li D, Bi C, Iqbal J.
europepmc   +1 more source

Pro‐Organic by Design: Choice Architecture Shaping Online Organic Grocery Purchases

Business Strategy and the Environment, EarlyView.
ABSTRACT Consumer uptake of organic food is shaped by both personal values and the way choices are structured in the retail environment. Unlike prior research, we here investigate how elements of supermarket choice architecture influence organic choices.
John Thøgersen, Darius‐Aurel Frank, Jessica Aschemann‐Witzel   +2 more
wiley   +1 more source

Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides for Safe and Effective mRNA Delivery <i>In Vitro</i> and <i>In Vivo</i>. [PDF]

ACS Appl Mater Interfaces
He Y, Wang L, Velayutham R, Valerio TI, Ricketts SD, Sun Y, Annan AC, Bowman J, Tran T, Mohammadnejad M, Liu K, Chen WR, Green DE, Fung KM, DeAngelis PL, Wilhelm S.   +15 more
europepmc   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

Biotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan, Fatemeh Najafi, Ziqiao Wang, Andrew L. Zydney   +3 more
wiley   +1 more source

From cheek to ureter: initial experience and learning curve of single-port robotic buccal mucosa graft ureteroplasty for complex strictures. [PDF]

J Robot Surg
Qi JC, Yang HX, Wang DB, Tang S, Wang RL, Santodirocco L, Alkassis M, Calvo RS, Xue WY, Wang YX, Crivellaro S.   +10 more
europepmc   +1 more source