Functional impairment of human resident cardiac stem cells by the cardiotoxic antineoplastic agent trastuzumab [PDF]
Trastuzumab (TZM), a monoclonal antibody against the ERBB2 protein, increases survival in ERBB2-positive breast cancer patients. Its clinical use, however, is limited by cardiotoxicity. We sought to evaluate whether TZM cardiotoxicity involves inhibition
A. c. Wolff +12 more
core +1 more source
Pegasis Double Cluster Head Hybrid Congestion Control in Wireless Sensor Networks
Wireless sensor network (WSN) is the fastest growing technology that dominates the future world into wireless communication. It is a collection of a number of self-governing sensor nodes responsible to sense, process and manipulate the nodes.
Abdul Ali, M. Vadivel
doaj +1 more source
A Review on Energy Consumption Optimization Techniques in IoT Based Smart Building Environments [PDF]
In recent years, due to the unnecessary wastage of electrical energy in residential buildings, the requirement of energy optimization and user comfort has gained vital importance.
Fayaz, Muhammad +4 more
core +2 more sources
Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression. [PDF]
Granulocyte-macrophage colony-stimulating factor (GM-CSF) produced by T helper 17 (Th17) cells plays an essential role in autoimmune diseases. Transcriptional regulation of Th17 cell differentiation has been extensively studied, but post-transcriptional ...
Adamiak, William +5 more
core +3 more sources
High-throughput
Background Plant transformation is an invaluable tool for basic plant research, as well as a useful technique for the direct improvement of commercial crops. Barley (Hordeum vulgare) is the fourth most abundant cereal crop in the world.
Snape John W +4 more
doaj +1 more source
Self-Synchronization in Duty-cycled Internet of Things (IoT) Applications
In recent years, the networks of low-power devices have gained popularity. Typically these devices are wireless and interact to form large networks such as the Machine to Machine (M2M) networks, Internet of Things (IoT), Wearable Computing, and Wireless ...
McCann, Julie A. +2 more
core +1 more source
The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons [PDF]
open access articleHerpes simplex virus 1 (HSV-1) establishes life-long latent infection within sensory neurons, during which viral lytic gene expression is silenced.
Coleman, Heather M. +7 more
core +3 more sources
Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]
Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S. +7 more
core +2 more sources
The evolution of the Internet of things (IoT) led to connect billions of heterogeneous physical devices together to improve the quality of human life by collecting data from their environment.
Abed et al.
doaj +1 more source
A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs. [PDF]
mRNA 3' end processing is an essential step in gene expression. It is well established that canonical eukaryotic pre-mRNA 3' processing is carried out within a macromolecular machinery consisting of dozens of trans-acting proteins. However, it is unknown
Ding, Junjun +14 more
core +1 more source

