Results 211 to 220 of about 900,751 (332)

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Calcium and aluminum-based fillers as flame-retardant additives in silicone matrices. III. Investigations on fire reaction

, 2013
Siska Hamdani-Devarennes, Claire Longuet, Rodolphe Sonnier, François Ganachaud, José‐Marie Lopez‐Cuesta   +4 more
openalex   +2 more sources

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Analysis of the initial spray from canonical fire suppression nozzles

, 2007
Ning Ren
openalex   +1 more source

Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation). [PDF]

Elife
Isbister JB, Ecker A, Pokorny C, Bolaños-Puchet S, Egas Santander D, Arnaudon A, Awile O, Natali BZ, Alonso JB, Boci E, Chindemi G, Courcol JD, Damart T, Delemontex T, Dietz A, Ficarelli G, Gevaert M, Herttuainen J, Ivaska G, Ji W, Keller D, King J, Kumbhar P, Lapere S, Litvak P, Mandge D, Muller EB, Pereira F, Planas J, Ranjan R, Reva M, Romani A, Rössert C, Schürmann F, Sood V, Teska A, Tuncel A, Van Geit W, Wolf M, Markram H, Ramaswamy S, Reimann MW.   +41 more
europepmc   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Slow-firing mode reduces stump oozing during pulmonary vessel stapling. [PDF]

J Thorac Dis
Kohama T, Tanahashi M, Yukiue H, Yamada T, Suzuki E, Yoshii N, Watanabe T, Tsuchida H, Shibata K, Endo T.   +9 more
europepmc   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Re-fire and not re-tire (III)

, 1988
Del and Marge Green
openalex   +1 more source

Solar-Assisted High-Efficiency Safe Cleanup of Viscous Crude Oil Spill by Superhydrophobic Fire Retardant Polyurethane Foam

Ying Wang, Jianhao Zhu, Hao Chang, Yili Duan, Jihang Wang, Zhihui Liu, Xilei Chen, Menghe Zhu, Pingan Song, Lei Liu   +9 more
openalex   +1 more source