Results 221 to 230 of about 900,751 (332)
Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum. [PDF]
Ejdrup A +7 more
europepmc +1 more source
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Layer V Neocortical neurons from individuals With drug-resistant epilepsy show multiple synaptic alterations but lack somatic hyperexcitability. [PDF]
Márquez LA +8 more
europepmc +1 more source
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang +13 more
wiley +1 more source
The Synaptic and Intrinsic Cellular Mechanisms of Persistent Firing in Neurogliaform Cells. [PDF]
Chen S +7 more
europepmc +1 more source
A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin +4 more
wiley +1 more source
Multi-ignition fire complexes drive extreme fire years and impacts
Rebecca C. Scholten +12 more
openalex +1 more source

