Results 51 to 60 of about 1,340,805 (345)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Firing Temperature of Romanesque Brick from Pác

Selected Scientific Papers: Journal of Civil Engineering, 2012
A pavement brick taken from a Romanesque part of the church in Pác, in the Trnava County, Slovakia, was investigated by x-ray diffraction analysis (XRD) and thermal analyses as differential thermal analysis (DTA), thermogravimetry (TG) and ...
Podoba Rudolf, Štubňa Igor, Lukovičová Jozefa, Bačík Peter   +3 more
doaj   +1 more source

Functional characterization of cannabidiol effect on the serotonergic neurons of the dorsal raphe nucleus in rat brain slices

Frontiers in Pharmacology, 2022
Cannabidiol (CBD), the main non-psychoactive cannabinoid found in the cannabis plant, elicits several pharmacological effects via the 5-HT1A receptor. The dorsal raphe nucleus (DRN) is the main serotonergic cluster in the brain that expresses the 5-HT1A ...
Aitziber Mendiguren, Erik Aostri, Elena Alberdi, Alberto Pérez-Samartín, Joseba Pineda   +4 more
doaj   +1 more source

A theoretical model of neuronal population coding of stimuli with both continuous and discrete dimensions

, 2001
In a recent study the initial rise of the mutual information between the firing rates of N neurons and a set of p discrete stimuli has been analytically evaluated, under the assumption that neurons fire independently of one another to each stimulus and ...
A. Treves, A. Treves, A. Treves, A. Treves, Alessandro Treves, C. Shannon, E. T. Rolls, E. T. Rolls, H. S. Seung, I. Samengo, L. M. Optican, L. M. Optican, M. Mezard, S. Panzeri, S. Panzeri, S. Panzeri, Valeria Del Prete, W. Bialek   +17 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Rocha com espodumênio como fundente para massas cerâmicas tradicionais Spodumene rock as a flux for traditional ceramic bodies

Cerâmica, 2010
Investigou-se a atuação de uma rocha com espodumênio como fundente em massas cerâmicas, analisando-se sua reatividade com outras matérias-primas, como quartzo e caulim.
S. R. Bragança, H. C. M. Lengler, C. P. Bergmann   +2 more
doaj   +1 more source

Experimental and Computational Study of Thermal Processes in Red Clays Exposed to High Temperatures

Energies, 2020
Fired bricks represent one of the most popular building materials, of which production is still growing. Since the functional properties of bricks have reached their physical limits, the current development aims at an optimization of production ...
Václav Kočí, Lenka Scheinherrová, Jiří Maděra, Martin Keppert, Zbigniew Suchorab, Grzegorz Łagód, Robert Černý   +6 more
doaj   +1 more source

Firing Behavior of the Clay Fraction of a Natural Kaolinitic Clay: Are They Different? [PDF]

Materials Research, 2019
A comparative investigation on the firing behavior of a natural kaolinitic clay from Campos dos Goytacazes, Brazil, and its specific clay fraction was performed. The clay fraction, equivalent diameter less than 2 µm, was separated from the precursor clay
Carlos Maurício Fontes Vieira, Sergio Neves Monteiro   +1 more
doaj   +2 more sources

Simulation of sintering ceramics based on Master Sintering Curve

Nihon Kikai Gakkai ronbunshu, 2021
In this paper, a simple simulation strategy for sintering ceramics is proposed by referring to the experimental results of the deformation profile obtained from a thermomechanical analysis (TMA) under uniaxial compression loads.
Chikako NATSUMEDA, Kazumi MATSUI, Junichi TATAMI, Takahiro YAMADA   +3 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source