Results 51 to 60 of about 2,833,474 (310)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
An examination of the relationship between firm size and export activity in the New Zealand lumber industry : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies, Massey University [PDF]
, 1993 This thesis explores the relationship between export activity and firm size, with specific reference to New Zealands lumber industry. The main purpose of this investigation is to identify firm characteristics which link firm size to export behavior. This
Craw, Michael Curtis
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Economic Liberalization in Nepal: Determinants, Structure, and Trends of FDI
Journal the Winners, 2017 This research examined the relationship between FDI (Foreign Direct Investment) and GDP (Gross Domestic Product) along with the impact of FDI determinants on FDI inflow in Nepal.
Raghu Bir Bista
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Assessing the firm performance through the financial ratios [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2011 The main objective of every firm is the creation of value, respectively the investment for which the efficiency resulted is above the profitability ratio required by the shareholders.
VASILESCU LAURA
doaj
Innovation and corporate dynamics: a theoretical framework [PDF]
, 2011 We provide a detailed analysis of a generalized proportional growth model (GPGM) of innovation and corporate dynamics that encompasses the Gibrat’s Law of Proportionate Effect and the Simon growth process as particular instances.
Growiec, Jakub +2 more
core
The Between Firm Effect with Multiproduct Firms [PDF]
Federal Reserve Bank of Dallas, Globalization and Monetary Policy Institute Working Papers, 2012 This paper studies multi-product firms with two factors of production: unskilled and skilled labor (talent). Creating new products is skill intensive while production is less skill intensive. We show here a new effect: an increase in the skilled labor supply, relatively to unskilled labor, could reduce the number of products but increase the average ...
openaire +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source