Results 81 to 90 of about 774,132 (309)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Law firm librarianship : issues, practice, and directions / [PDF]

open access: yes
The legal information environment is deep, wide, and dynamic with many participants, including courts, parliaments, legislatures, and administrative bodies. None exemplifies the agile, knowledge-engaging legal player better than the law firm.
Azzolini, John.
core  

Parish of Magdala [cartographic material] / [PDF]

open access: yes, 1947
Cadastral map of the Parish of Magdala. Relief shown by hachures.; Publication date based on latest date appearing in series. Sheet 116 "Proclaimed City of Blue Mountains 19th September 1947."; In top right corner: "Riding C."; Paper print in negative ...
H.E.C. Robinson (Firm)
core  

Private equity and venture capital financing in the Czech Republic and other european countries – development, opportunities and limitations

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2011
Financing by means of private equity and venture capital (PE/VC) offers businesses the resources required to finance their future growth and bring prospective business plans and innovative ideas to reality.
Jaroslava Rajchlová   +3 more
doaj   +1 more source

THE EFFECT OF ENTREPRENEURIAL MARKETING ORIENTATION ON COMPETITIVE ADVANTAGE WITH PERCIEVED MARKET TURBULANCE AS A MODERATOR IN THE EXPORT-ORIENTED FOREST PRODUCT INDUSTRY OF SOUTH KALIMANTAN, INDONESIA [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2022
Bundling resources from Market Orientation (MO), Entrepreneurial Orientation (EO) and Innovation Orientation (IO), and Customer Relationship Orientation (CRO) which are dimensions of Entrepreneurial Marketing Orientation (EMO) can be a source of ...
Helmi M., Naparin M.
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Portraits of Sarah Bernhardt as Marguerite Gautier in La Dame aux camelias [6] [picture] / [PDF]

open access: yes, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an10708528 ...
Falk Studios (Firm)
core  

Firm attributes and share price fluctuation of deposit money banks listed in Nigeria

open access: yesJurnal Ekonomi Modernisasi, 2019
This paper examined firms’ attributes impact on the fluctuation of share prices of listed deposit money banks in Nigeria. Ex-post facto research design was employed, and 13 deposit money banks firms were selected out of 15 from 2006-2016.
Adamu Adamu Idris   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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