Results 61 to 70 of about 82,602 (263)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Dimensions of human capital and firm performance: Micro-firm context
IIMB Management Review, 2018 The objective of the paper is twofold: first, to examine the dimensions of human capital with respect to a measurement model; second, to test the direct and mediating relationships between human capital dimensions and firm performance.
Eijaz Ahmed Khan, Mohammed Quaddus
doaj +1 more source
Innovation strategies and firm performance
Journal of Productivity AnalysisAbstractInnovation is often seen as crucial for firm survival and as a way for firms to differentiate themselves from their rivals. However, innovation studies are vague about the actual importance of different innovation strategies. In this study, we distinguish between pure product, process, organizational, and marketing innovations and their ...
Peter Bogetoft +3 more
openaire +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
The Effect of Board Characteristics on Firm Performance in Japan
East Asian Economic Review, 2009 This paper analyzes the effect of similarity among board members on firm performance in Japanese manufacturing firms. The similarity measures regarding age and educational background of individual directors were used to predict firm performance.
Oona Cha , Taehun Jung
doaj +1 more source
Efficacy of firm size and structure on organizational performance [PDF]
Економіка та управління АПКFirm size plays an important role in determining firm’s performance even though it’s not clear whether firm size affect organizational perfor[1]mance. Therefore; an investigation is required to assess the effect firm size and structure will have on firm ...
OLALEKAN OWOTUTU SABITU +2 more
doaj +1 more source
, 2019 Tujuan penulisan jurnal ini untuk mengidentifikasi kinerja perusahaan dan metode pengukurannya. Setiap perusahaan pasti mempunyai tujuan utama. Guna mencapai tujuan utama tersebut membutuhkan banyak faktor penunjang. Salah satu faktor yang penting adalah kinerja perusahaan.
openaire +2 more sources
Sustainability reporting and firm performance
Pressacademia, 2019 Purpose- The aim of this paper is to examine sustainability reporting and its relation with firm performance. We investigate whether such reporting practices improve the firm value while enhancing its profitability and the financial leverage impact on sustainability reporting in the automotive industry.
KAYA, İdil, HALİT AKBULUT, Destan
openaire +3 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source