Results 71 to 80 of about 129,552 (313)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Partial Privatization and Firm Performance [PDF]
ABSTRACTMost privatization programs begin with a period of partial privatization in which only non‐controlling shares of firms are sold on the stock market. Since management control is not transferred to private owners it is widely contended that partial privatization has little impact.
openaire +2 more sources
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Dimensions of human capital and firm performance: Micro-firm context
The objective of the paper is twofold: first, to examine the dimensions of human capital with respect to a measurement model; second, to test the direct and mediating relationships between human capital dimensions and firm performance.
Eijaz Ahmed Khan, Mohammed Quaddus
doaj +1 more source
Sustainability reporting and firm performance
Purpose- The aim of this paper is to examine sustainability reporting and its relation with firm performance. We investigate whether such reporting practices improve the firm value while enhancing its profitability and the financial leverage impact on sustainability reporting in the automotive industry.
KAYA, İdil, HALİT AKBULUT, Destan
openaire +3 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Effect of Board Characteristics on Firm Performance in Japan
This paper analyzes the effect of similarity among board members on firm performance in Japanese manufacturing firms. The similarity measures regarding age and educational background of individual directors were used to predict firm performance.
Oona Cha , Taehun Jung
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Impact of human resource slacks on firm performance: Evidence from a developing country [PDF]
Purpose of this paper is to investigate whether HR slack leads to improve firm performance, and what is the impact of HR slack in absolute and in relative terms on firm performance in a developing country.
M.M. Fonseka +2 more
doaj
Efficacy of firm size and structure on organizational performance [PDF]
Firm size plays an important role in determining firm’s performance even though it’s not clear whether firm size affect organizational perfor[1]mance. Therefore; an investigation is required to assess the effect firm size and structure will have on firm ...
OLALEKAN OWOTUTU SABITU +2 more
doaj +1 more source

