Results 31 to 40 of about 173,044 (261)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis of Firm Value in Companies Listed in the LQ45 Index

Indonesian Interdisciplinary Journal of Sharia Economics
This research aims to analyze the effect of profitability and liquidity on firm value with firm size as a moderating variable. The population of this research is 60 companies listed on the LQ45 index for the 2019-2022 period.
Firmansyach Maulana Hariyono, Dhani Ichsanuddin Nur   +1 more
doaj   +1 more source

Firm size and profitability in supporting firm value through earnings management [PDF]

New Applied Studies in Management, Economics & Accounting
A decline in stock prices indicates a reduction in firm value for several manufacturing companies. This situation can cause investors to reconsider making investments.
Ait Novatiani, Veronica Christina, Bachtiar Asikin, Robertus Ary Novianto, Tetty Lasniroha Sarumpet, Aida Wijaya   +5 more
doaj   +1 more source

THE EFFECT OF GROWTH OPPORTUNITY, FIRM SIZE, AND DEBT POLICY ON FIRM VALUE MEDIATED BY PROFITABILITY IN REAL ESTATE AND PROPERTY SECTOR COMPANIES ON THE INDONESIA STOCK EXCHANGE

Russian Journal of Agricultural and Socio-Economic Sciences, 2021
The purpose of this study is to obtain empirical evidence regarding the effect of Growth Opportunity, Firm Size, and Debt Policy on Firm Value, and examine the role of Profitability in mediating the effect of Growth Opportunity, Firm Size, and Debt ...
Janitra P.V.V., Sedana I.B.P.
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

THE EFFECT OF FIRM PERFORMANCE, LEVERAGE, FIRM SIZE, AND FIRM GROWTH ON AGENCY COST OF TRADING COMPANY IN INDONESIA, MALAYSIA, AND THAILAND: RESEARCH PERIOD OF 2009 – 2013

Jurnal Riset Manajemen Sains Indonesia, 2017
In this study,the author investigate the relationship of firm performance, leverage, firm size, and firm growth on the agency cost. In the company’s life, there are several holders an important role in the company itself.
Hamidah Hamidah, Ari Wicaksono, Gatot Nazir Ahmad   +2 more
doaj   +1 more source

PENGARUH DEBT TO EQUITY RATIO DAN FIRM SIZE TERHADAP NILAI PERUSAHAAN DENGAN RETURN ON EQUITY SEBAGAI VARIABEL INTERVENING PADA PERUSAHAAN YANG TERDAFTAR DI JAKARTA ISLAMIC INDEX (JII) PERIODE 2016-2018

I-Finance, 2020
The Study investigated the influence of Debt to Equity Ratio and Firm Size on Firm Value with Return On Equity as intervening variables in Jakarta Islamic Index (JII) in 2016-2018.
Indah Khairunnisa, Mismiwati Mismiwati, Bunga Mar’atush Shalihah   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Firm Size, Competition, Financing and Innovation

International Journal of Management and Economics, 2014
This paper investigates the effects of firm size, competition and access to finance on the innovation performance of that firm. After a review of the relevant literature, three logit models are proposed and tested.
Alsharkas Zeina
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source