Results 41 to 50 of about 1,527,256 (305)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Firm size distortions under duopoly
Estudios de Economía, 2017 Motivated by the fact that some regulations involve extra costs for those firms at a size beyond a critical threshold, this paper contributes to the analysis of the welfare distortions due to these regulations.
Miguel González-Maestre +1 more
doaj
IJEBD (International Journal of Entrepreneurship and Business Development)Purpose: This study aims to analyze the effect of CSR and profitability on firm value in the mining sub-sector listed on the IDX for the period 2020-2023.
Peby Rahayu, Tendi Yanuar, Acep Komara
doaj +1 more source
Do Foreign Ownership, Financial Leverage, Inflation and Firm Size Influence to Firm Value ? Evidence in Indonesia Stock Exchange [PDF]
, 2018 The aim of this study is to get empirical proof the influence of foreign ownership, financial leverage, Inflation, firm size and firm value of firms listed in Indonesia Stock Exchange (IDX).
Sari, P. P. (Pristin)
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Indonesian Interdisciplinary Journal of Sharia EconomicsThis research is based on the fact that many companies ignore the environment in their operations, although good relationships with the community and the environment are vital for business sustainability.
Faiz Firdaus Makarim +2 more
doaj +1 more source
Firm Size, Competition, Financing and Innovation
International Journal of Management and Economics, 2014 This paper investigates the effects of firm size, competition and access to finance on the innovation performance of that firm. After a review of the relevant literature, three logit models are proposed and tested.
Alsharkas Zeina
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
COMPANY VALUE DETERMINANTS STUDY ON MANUFACTURING COMPANY LISTED IN INDONESIA STOCK EXCHANGE
Jema: Jurnal Ilmiah Bidang Akuntansi dan Manajemen, 2017 The purpose of this study to determine the effect of firm size, leverage, and profitability to the value of companies in manufacturing companies listed on the Indonesia Stock Exchange (BEI) partially or simultaneously. This research tested the hypothesis
Oyong Lisa
doaj +1 more source