Results 41 to 50 of about 1,523,391 (358)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Analysis of Firm Value in Companies Listed in the LQ45 Index
Indonesian Interdisciplinary Journal of Sharia EconomicsThis research aims to analyze the effect of profitability and liquidity on firm value with firm size as a moderating variable. The population of this research is 60 companies listed on the LQ45 index for the 2019-2022 period.
Firmansyach Maulana Hariyono +1 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Firm size distortions under duopoly
Estudios de Economía, 2017 Motivated by the fact that some regulations involve extra costs for those firms at a size beyond a critical threshold, this paper contributes to the analysis of the welfare distortions due to these regulations.
Miguel González-Maestre +1 more
doaj
Indonesian Interdisciplinary Journal of Sharia EconomicsThis research is based on the fact that many companies ignore the environment in their operations, although good relationships with the community and the environment are vital for business sustainability.
Faiz Firdaus Makarim +2 more
doaj +1 more source
Firm Size, Competition, Financing and Innovation
International Journal of Management and Economics, 2014 This paper investigates the effects of firm size, competition and access to finance on the innovation performance of that firm. After a review of the relevant literature, three logit models are proposed and tested.
Alsharkas Zeina
doaj +1 more source
COMPANY VALUE DETERMINANTS STUDY ON MANUFACTURING COMPANY LISTED IN INDONESIA STOCK EXCHANGE
Jema: Jurnal Ilmiah Bidang Akuntansi dan Manajemen, 2017 The purpose of this study to determine the effect of firm size, leverage, and profitability to the value of companies in manufacturing companies listed on the Indonesia Stock Exchange (BEI) partially or simultaneously. This research tested the hypothesis
Oyong Lisa
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The Effect of Good Corporate Governance Towards Idiosyncratic Risk
Manajemen dan Bisnis, 2020 This study aims to analyze the effect of good corporate governance towards idiosyncratic risk as a proxy with corporate governance variable as board size, independent director, women, firm size, firm performance, and firm age.
Cintya Yuliana Limantara +2 more
doaj +1 more source