Results 41 to 50 of about 1,519,482 (308)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
IJEBD (International Journal of Entrepreneurship and Business Development)Purpose: This study aims to analyze the effect of CSR and profitability on firm value in the mining sub-sector listed on the IDX for the period 2020-2023.
Peby Rahayu, Tendi Yanuar, Acep Komara
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Firm size distortions under duopoly
Estudios de Economía, 2017 Motivated by the fact that some regulations involve extra costs for those firms at a size beyond a critical threshold, this paper contributes to the analysis of the welfare distortions due to these regulations.
Miguel González-Maestre +1 more
doaj
Indonesian Interdisciplinary Journal of Sharia EconomicsThis research is based on the fact that many companies ignore the environment in their operations, although good relationships with the community and the environment are vital for business sustainability.
Faiz Firdaus Makarim +2 more
doaj +1 more source
Firm Size, Competition, Financing and Innovation
International Journal of Management and Economics, 2014 This paper investigates the effects of firm size, competition and access to finance on the innovation performance of that firm. After a review of the relevant literature, three logit models are proposed and tested.
Alsharkas Zeina
doaj +1 more source
COMPANY VALUE DETERMINANTS STUDY ON MANUFACTURING COMPANY LISTED IN INDONESIA STOCK EXCHANGE
Jema: Jurnal Ilmiah Bidang Akuntansi dan Manajemen, 2017 The purpose of this study to determine the effect of firm size, leverage, and profitability to the value of companies in manufacturing companies listed on the Indonesia Stock Exchange (BEI) partially or simultaneously. This research tested the hypothesis
Oyong Lisa
doaj +1 more source
The Effect of Good Corporate Governance Towards Idiosyncratic Risk
Manajemen dan Bisnis, 2020 This study aims to analyze the effect of good corporate governance towards idiosyncratic risk as a proxy with corporate governance variable as board size, independent director, women, firm size, firm performance, and firm age.
Cintya Yuliana Limantara +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source