Results 81 to 90 of about 29,704,411 (288)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

First-Order Saddlepoint Approximation for Reliability Analysis

open access: yes, 2004
In the approximation methods of reliability analysis, nonnormal random variables are transformed into equivalent standard normal random variables. This transformation tends to increase the nonlinearity of a limit-state function and, hence, results in ...
Sudjianto, Agus, Du, Xiaoping
core   +1 more source

The system reliability of steel trusses with correlated variables [PDF]

open access: yesArchives of Civil Engineering
The paper focuses on the system reliability of steel trusses with correlated variables. The correlation between bearing capacities of bars was considered. Two static truss schemes were considered. Nodal forces were the only load.
Katarzyna Kubicka, Urszula Radon
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Structural Reliability of Jacket Platforms using Second Order Reliability Method [PDF]

open access: yes, 2015
Jacket platform is the base structure for offshore oil processing topside structure which is used for continuous processing of crude oil. However, jacket platforms are subject to very harsh environments, subjected to extreme and operational conditions ...
Wan, Yin Huan
core   +1 more source

A Unified Probabilistic Framework for the Reliability and Robustness Assessment of Series Structural Systems: Axiomatic Foundations and Computational Approximations

open access: yesMathematics
This paper develops a unified probabilistic framework for the simultaneous assessment of reliability and robustness of series structural systems. Part I formulates an axiomatic theory of structural robustness: the robustness factor Frob is defined as the
Dean Čizmar   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Quantile-Based First-Order Second-Moment Method for Efficient Slope Reliability Analysis

open access: yes, 2023
The slope system unavoidably contains many uncertainties. These uncertainties can be effectively taken into account by probabilistic analysis methods. In the present paper, a quantile-based first-order second-moment method (QFOSM) is applied to efficient
Yang, Zhiyong   +3 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Closed-Form Design Quantiles Under Skewness and Kurtosis: A Hermite Approach to Structural Reliability

open access: yesMathematics
A Hermite-based framework for reliability assessment within the limit state method is developed in this paper. Closed-form design quantiles under a four-moment Hermite density are derived by inserting the Gaussian design quantile into a calibrated cubic ...
Zdeněk Kala
doaj   +1 more source

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