Results 81 to 90 of about 1,101,220 (313)
Background The 2023 Kahramanmaraş earthquakes, one of Turkey’s most devastating disasters, highlighted the importance of effective disaster response operations.
Hüseyin Koçak +5 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
First aid training in driving schools - uselessness or relevant measure with considerable potential? [PDF]
Despite various traffic safety measures traffic accidents still happen. In the Czech Republic, 57 serious accidents happen every day. In situation of accident, immediate help of the bystanders can save lives and reduce damage.
Petr Zámečník +3 more
doaj
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
First aid atau pertolongan pertama merupakan salah satu bantuan yang diberikan kepada korban kecelakaan baik kecelakaan lalu lintas maupun bencana alam. Kita ketahui bersama bahwa indonesia termasuk negara yang tidak terlepas dari musibah dan bencana alam setiap tahun.
Noni, Mektilde +3 more
openaire +2 more sources
PP39. 5-AMINOLEVULINIC ACID AIDED RESECTION OF PAEDIATRIC BRAIN TUMOURS: THE UK’S FIRST CASE SERIES [PDF]
Ms Charlotte Burford +11 more
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
This is the third Cochrane Corner in the International Journal of First Aid Education, provided to you by Cochrane First Aid. Like any Cochrane Corner, it summarizes the findings of a Cochrane systematic review.
Jorien Laermans, Tine D'aes
doaj +2 more sources

