Results 41 to 50 of about 1,867,774 (297)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Penetrating Lung Injury Caused by a Close-range Blank Cartridge: Case Report

open access: yesİstanbul Medical Journal, 2019
A 17-year-old male was brought to the emergency department with chest injury by a gunshot from a blank cartridge (BC). No bullet or fragment was seen in the radiological examination. The patient underwent left thoracotomy for hemopneumothorax.
Saniye Göknil Çalık   +4 more
doaj   +1 more source

Pleural fluid penetration of moxifloxacin and doripenem: An experimental model of empyema

open access: yesİstanbul Kuzey Klinikleri, 2020
OBJECTIVE: This study aimed to evaluate the penetration of moxifloxacin and doripenem into the pleural fluid (PF) using a rabbit model of empyema. METHODS: An empyema was induced using the intrapleural injection of turpentine (1 mL), followed 24 h later ...
Mustafa Calik   +4 more
doaj   +1 more source

How to evaluate first aid skills after training: a systematic review

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2022
Background To be able to help and save lives, laypersons are recommended to undergo first aid trainings. The aim of this review was to explore the variety of the elements of the measuring systems to assess the effects of first aid trainings on different ...
Sihvo Minna   +2 more
doaj   +1 more source

Knowledge and attitude of paediatric first aid among elementary schoolteachers in Jeddah, Saudi Arabia

open access: yesJournal of Family Medicine and Primary Care, 2022
Introduction: Children at schools are at risk of getting injuries during their activities. In the absence of medical support and delays in ambulance arrival, teachers are the first responders to provide first aid when accidents occur.
Maher Alsulami   +8 more
doaj   +1 more source

Knowledge attitude and practices of undergraduate students regarding first aid measures [PDF]

open access: yes, 2010
OBJECTIVES: To assess knowledge, attitude and practices of first aid measures in undergraduate students of Karachi. METHODS: A cross-sectional study was carried out at six colleges of Karachi, three of which were medical colleges and three non-medical ...
Khan, Afrasyab   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Clinically Significant Thyroid Metastasis of Lung Cancer: A Rare Case Report

open access: yesİstanbul Medical Journal, 2017
Although thyroid tumors are commonly primary, metastases are extremely rare. We report a rare case of metastatic adenocarcinoma of primary lung origin presenting as a solitary thyroid nodule. A 55-yearold female housewife with no significant past medical
Mustafa Çalık   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Chylothorax: A Rare Complication of Endoscopic Thoracic Sympathectomy

open access: yesİstanbul Medical Journal, 2018
Hyperhidrosis (HH) is a pathological condition of excessive secretion of the eccrine sweat glands in amounts greater than that required for physiological needs.
Mustafa Çalık   +3 more
doaj   +1 more source

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