Results 71 to 80 of about 6,363,291 (243)

Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China

Infection and Drug Resistance, 2022
Bin Lu,1 Yunzhen Shi,1 Yangxiao Zhou,2 Fenhua Zhao,3 Mengqi Wang,4 Xinling Pan5 1Department of Infectious Diseases, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 2Department of Clinical Laboratory ...
Lu B, Shi Y, Zhou Y, Zhao F, Wang M, Pan X   +5 more
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Analysing the challenges for large public libraries in the twenty-first century: A case study of the State Library of Victoria in Australia

, 2008
For large public libraries, the development of digital technologies poses challenges that have yet to be fully explored. While library sector rhetoric rightly imagines that digital technologies bring change to all aspects of library operations, it is not
McShane, Ian, Ian McShane, Vivienne Waller, Waller, Vivienne   +3 more
core  

Seeding activity of skin misfolded tau as a biomarker for tauopathies

Molecular Neurodegeneration
Background Tauopathies are a group of age-related neurodegenerative diseases characterized by the accumulation of pathologically hyperphosphorylated tau protein in the brain, leading to prion-like aggregation and propagation.
Zerui Wang, Ling Wu, Maria Gerasimenko, Tricia Gilliland, Zahid Syed Ali Shah, Evalynn Lomax, Yirong Yang, Steven A. Gunzler, Vincenzo Donadio, Rocco Liguori, Bin Xu, Wen-Quan Zou   +11 more
doaj   +1 more source

Surgery-first orthognathic approach case series: Salient features and guidelines

Journal of Orthodontic Science, 2016
Conventional orthognathic surgery treatment involves a prolonged period of orthodontic treatment (pre- and post-surgery), making the total treatment period of 3-4 years too exhaustive.
Narayan H Gandedkar, Chai Kiat Chng, Winston Tan   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Well-reasoned opinion? Critical analysis of the first case against the alleged senior leaders of the Khmer Rouge (case 002/01) [PDF]

, 2015
For more about the East-West Center, see http://www.eastwestcenter.org/On 7 August 2014, the Extraordinary Chambers in the Courts of Cambodia (ECCC) reached an important institutional milestone when the Court published its long-awaited Trial Judgment in ...
Cohen, David, Hyde, Melanie, Van Tuyl, Penelope, Fung, Stephanie   +3 more
core  

Coordinated activation of DNMT3a and TET2 in cancer stem cell-like cells initiates and sustains drug resistance in hepatocellular carcinoma

Cancer Cell International
Background Resistance to targeted therapies represents a significant hurdle to successfully treating hepatocellular carcinoma (HCC). While epigenetic abnormalities are critical determinants of HCC relapse and therapeutic resistance, the underlying ...
Tao Cheng, Changli Zhou, Sicheng Bian, Kelsey Sobeck, Yahui Liu   +4 more
doaj   +1 more source

The Indian Silverbill Euodice malabarica: a new exotic breeding species for the Italian avifauna?

Rivista Italiana di Ornitologia - Research in Ornithology
The first confirmed breeding case of the Indian Silverbill Euodice malabarica in Italy is reported. We also report the new Italian records and the implications on the expansion of the species from southern France, where the species is naturalised from ...
Enrico Carta, Elan Federico Zucchetti, Rudy Valfiorito, Niccolò Alberti   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source