Results 11 to 20 of about 84,035 (262)

Comparison of serum kynurenine pathway metabolites between patients with first-episode and recurrent major depressive disorder

Sichuan jingshen weisheng, 2023
BackgroundThe pathogenesis of depression remains not fully understood， and previous studies have suggested that the kynurenine pathway （KP） plays an important role in the pathogenesis of major depressive disorder.ObjectiveTo study the difference in serum
Lao Guohui, Ning Yuping, Zhou Yanling
doaj   +1 more source

Altered functional connectivity in first-episode and recurrent depression: A resting-state functional magnetic resonance imaging study

Frontiers in Neurology, 2022
BackgroundFunctional magnetic resonance imaging (fMRI) studies examining differences in the activity of brain networks between the first depressive episode (FDE) and recurrent depressive episode (RDE) are limited.
Jifei Sun, Zhongming Du, Yue Ma, Limei Chen, Zhi Wang, Chunlei Guo, Yi Luo, Deqiang Gao, Yang Hong, Lei Zhang, Ming Han, Jiudong Cao, Xiaobing Hou, Xue Xiao, Jing Tian, Xue Yu, Jiliang Fang, Yanping Zhao   +17 more
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Neural basis of recollection in first‐episode major depression [PDF]

Human Brain Mapping, 2012
AbstractBackground. Patients with major depressive disorder (MDD) display impairments in recollection, which have been explained by both hippocampal and prefrontal dysfunction. Here, we used an event‐related fMRI design, to dissociate hippocampal and prefrontal contributions to the neural processes involved in recollection success and recollection ...
van Eijndhoven, P.F., van Eijndhoven, P.F., van Wingen, G.A., Fernandez, G.S.E., Rijpkema, M.J.P., Pop-Purceleanu, M., Verkes, R.J., Buitelaar, J.K., Buitelaar, J.K., Tendolkar, I.   +9 more
openaire   +3 more sources

The Association Between Suicide Attempts, Anxiety, and Childhood Maltreatment Among Adolescents and Young Adults With First Depressive Episodes

Frontiers in Psychiatry, 2021
Objective: Adolescents and young adults are susceptible to high-risk behaviors such as self-harm and suicide. However, the impact of childhood maltreatment on suicide attempts in adolescents and young adults with first episode of depression remains ...
Hui Chen, Wen Li, Xia Cao, Peiqu Liu, Jiali Liu, Xianliang Chen, Chenyuli Luo, Xiaoxi Liang, Huijuan Guo, Shaoling Zhong, Xiaoping Wang, Jiansong Zhou   +11 more
doaj   +1 more source

Prevalence and correlates of dyslipidemia in first-episode and drug-naïve major depressive disorder patients with comorbid abnormal glucose metabolism: Sex differences

Frontiers in Psychiatry, 2023
BackgroundLipid metabolism is associated with glucose metabolism, but whether there are variations between sexes in risk factors and prevalence of abnormal lipid metabolism in major depressive disorder (MDD) patients with glucose metabolism abnormalities
Quanfeng Zhu, Quanfeng Zhu, Yali Zheng, XiaoE Lang, Zhengchuang Fu, Peng Zhang, Guojun Jiang, Xiangyang Zhang, Xiangyang Zhang   +8 more
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OVERWEIGHT AND OBESITY: FREQUENCY AND CORRELATES AMONG THE PATIENTS OF FIRST EPISODE OF DEPRESSION

Pakistan Armed Forces Medical Journal, 2020
Objective: To study the magnitude and correlates of overweight and obesity among the patients presenting with first episode of depression at a teaching hospital of Azad Jammu and Kashmir. Study Design: Correlational study.
Syed Azhar Ali Kazmi, Abdul Quddus, Muhammad Fareed Khan, Faisal Naveed, Syeda Misbah Batool   +4 more
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Association between acute critical life events and the speed of onset of depressive episodes in male and female depressed patients

BMC Psychiatry, 2018
Background A series of studies indicate that a fast onset of a depressive episode (within 7 days) is a clinical variable useful for indicating bipolarity even when no manic episode has occurred to date.
Maria Strauss, Roland Mergl, Nora Gürke, Kerstin Kleinert, Christian Sander, Ulrich Hegerl   +5 more
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Serum Lipid Levels and Suicide Attempts Within 2 Weeks in Patients With Major Depressive Disorder: Is There a Relationship?

Frontiers in Psychiatry, 2021
The potential correlation between serum lipid profiles and suicidal tendencies has been previously reported, however, it is unclear whether serum lipid profiles have definite relevance to recently attempted suicides in individuals suffering from major ...
Siyao Zhou, Ke Zhao, Xiang Shi, Huankun Sun, Siyu Du, Xuemeng Miao, Jianjun Chen, Fan Yang, Minzhi Xing, Wang Ran, Jiaying Lao, Xiangyang Zhang, Xiangyang Zhang, Wei Wang, Wei Tang   +14 more
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Features Associated With Depressive Predominant Polarity and Early Illness Onset in Patients With Bipolar Disorder

Frontiers in Psychiatry, 2020
Objective: The aim of this study is to determine the prevalence of three possible diagnostic specifiers, namely predominant polarity (PP) throughout illness, polarity of the first episode and early age at onset, in a sample of bipolar disorder (BD ...
Jesús García-Jiménez, Luis Gutiérrez-Rojas, Luis Gutiérrez-Rojas, Luis Gutiérrez-Rojas, Sara Jiménez-Fernández, Sara Jiménez-Fernández, Pablo José González-Domenech, Pablo José González-Domenech, María D. Carretero, Manuel Gurpegui, Manuel Gurpegui   +10 more
doaj   +1 more source

Depression in first episode psychosis: The role of subordination and shame [PDF]

Psychiatry Research, 2014
Depression in early psychosis is linked to poor outcome, relapse and risk of suicide, yet remains poorly understood. This article aims to examine the development of depression in acute and post psychotic phases of first episode psychosis (FEP), and its relationship to persecutors, voices, insight, and recovery.
Rachel Upthegrove, Kerry Ross, Katerine Brunet, Richard McCollum, Lisa Jones   +4 more
openaire   +2 more sources