Results 71 to 80 of about 487,972 (266)

First Integrals and Invariants of Systems of Ordinary Differential Equations

Mathematics
We investigate the interplay between monomial first integrals, polynomial invariants of certain group action, and the Poincaré–Dulac normal forms for autonomous systems of ordinary differential equations with a diagonal matrix of the linear part.
Mateja Grašič, Abdul Salam Jarrah, Valery G. Romanovski   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Darboux Integrability Of the Biological System

Al-Rafidain Journal of Computer Sciences and Mathematics
In the given paper, we investigate the integrability of a mathematical model of a 3D biological system. Our results show that the system admits a polynomial first integrals for some parameters, an invariant algebraic surface with an exponential factor ...
Zakariya Hashem Ali, Ahmad Muhamad Husien   +1 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Hyperbolicity, transversality and analytic first integrals

Journal of Differential Equations, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Task-First or Context-First? Tool Integration Revisited [PDF]

2009 IEEE/ACM International Conference on Automated Software Engineering, 2009
If software engineering tools are not "properly integrated", they can reduce engineers' productivity. Associating and retrieving information scattered across the tools become unsystematic and inefficient. Our work provides empirical evidence on what is a "poor" and a "proper" tool integration, focusing on practitioners' perspectives.
openaire   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

First Integral Method for Systems of (1+1)-Dimensional Dispersive Long Wave

Walailak Journal of Science and Technology, 2014
The First Integral method (FIM) is applied to solve a dispersive long wave system. In this method the division theorem, as a statement in commutative Algebra has an important role.
Jafar BIAZAR, Mohamad Bagher MEHRLATIFAN
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source