Results 61 to 70 of about 13,280,617 (282)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

On the Linearization of Second-Order Ordinary Differential Equations to the Laguerre Form via Generalized Sundman Transformations

Symmetry, Integrability and Geometry: Methods and Applications, 2013
The linearization problem for nonlinear second-order ODEs to the Laguerre form by means of generalized Sundman transformations (S-transformations) is considered, which has been investigated by Duarte et al. earlier.
M. Tahir Mustafa, Ahmad Y. Al-Dweik, Raed A. Mara'beh   +2 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Chiellini Hamiltonian Lienard differential systems

Electronic Journal of Differential Equations, 2019
We characterize the centers of the Chiellini Hamiltonian Lienard second-order differential equations $x'=y$, $y'=-f(x) y -g(x)$ where $g(x)=f(x) (k - \alpha (1 +\alpha) \int f(x) dx )$ with $\alpha, k \in \mathbb{R}$.
Jaume Gine, Jaume Llibre, Claudia Valls
doaj  

The problem of first integral of nonholonomic systems

Vietnam Journal of Mechanics, 2001
In this paper, the problem of first integrals of a nonholonomic system is discussed. The aim of this work is concentra.ted on finding the condition for existence of first integrals.
Do Sanh
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

The First Mean Value Theorem for Integrals [PDF]

Formalized Mathematics, 2008
For simplicity, we use the following convention: X is a non empty set, S is a σ-field of subsets of X, M is a σ-measure on S, f , g are partial functions from X to R, and E is an element of S. One can prove the following three propositions: (1) If for every element x of X such that x ∈ dom f holds f(x) ≤ g(x), then g − f is non-negative.
Keiko Narita, Noboru Endou, Yasunari Shidama   +2 more
openaire   +1 more source

Estimates for multiple stochastic integrals and stochastic Hamilton-Jacobi equations [PDF]

, 2004
We study stochastic Hamilton-Jacobi-Bellman equations and the corresponding Hamiltonian systems driven by jump-type Lévy processes. The main objective of the present paper is to show existence, uniqueness and a (locally in time) diffeomorphism ...
Kolokoltsov, V. N. (Vasiliĭ Nikitich), Tyukov, Alexei E., Schilling, René L., Vassili Kolokol'tsov, Alexei Tyukov, Schilling, RL, Tyukov, AE, Tyukov, A.E., Kolokoltsov, VN, Kolokol'tsov, V.N., René Schilling   +10 more
core   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source