Results 71 to 80 of about 26,513 (266)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Meromorphic first integrals: some extension results [PDF]
Let \({\mathcal F}\) be a one-dimensional holomorphic foliation with possible isolated singularities on a complex surface \(M\). Such a foliation is given by a holomorphic vector field near each point of \(M\). By a theorem of \textit{A. Seidenberg} [J. Am. Math.
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Liouvillian first integrals of differential equations [PDF]
Liouvillian functions are functions that are built up from rational functions using exponentiation, integration, and algebraic functions. We show that if a system of differential equations has a generic solution that satisfies a liouvillian relation, that is, there is a liouvillian function of several variables vanishing on the curve defined by this ...
openaire +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
On the monotonicity of the quotient of certain abelian integrals
We prove that the quotient of abelian integrals associated to an elliptic surface is bounded and strictly increasing by first determining the Picard-Fuchs equation satisfied by the abelian integrals and the Riccati equation satisfied by the quotient of ...
Min Ho Lee
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Reduction Formulae of 2-refined Neutrosophic Integrals and their Applications [PDF]
The main aim of this manuscript is to establish for the first time the reduction formulae of 2-refined neutrosophic indefinite integrals (shortly, RF2RNII) which have double indeterminacy I1 and I2 respectably.
Florentin Smarandache +1 more
doaj +1 more source
All-order differential equations for one-loop closed-string integrals and modular graph forms
We investigate generating functions for the integrals over world-sheet tori appearing in closed-string one-loop amplitudes of bosonic, heterotic and type-II theories.
Jan E. Gerken +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

