Results 91 to 100 of about 975,233 (311)
Tamarix chinensis effectively prevents coastal erosion, stabilizes the surface of coastal wetlands, and improves the soil quality of saline-alkali land, playing a crucial role in coastal wetland ecosystem restoration.
Liying Zhu +8 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Kristin Comella,1 Walter Bell2 1US Stem Cell, Inc, Sunrise, FL, USA; 2South African Stem Cell Institute, Parys, South Africa Background: Stromal vascular fraction (SVF) is a mixture of cells which can be isolated from a mini-lipoaspirate of fat tissue ...
Comella K, Bell W
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Photograph - An elderly First Nations man wearing a headdress made of buffalo hide and horns, standing in front of a log cabin, likely ...
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The following essay deals with Plotinus’ metaphors of theatre in his work On Providence, which should clarify, what is and what should be the existence of man. The first metaphor presents the life of man through the image of an actor who understands that
Róbert Karul
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Od metafizyki do empirii. Antropologiczno-filozoficzne wizje człowieka [From metaphysics to empiricism. Philosophical anthropology on man] [PDF]
This essay focuses on three conceptions of man formulated within the German school of philosophical anthropology. I discuss, one by one, theories by Max Scheler, Helmuth Plessner and Arnold Gehlen.
Karol Chrobak
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Daniel Freeman as an older man, circa 1904. He was claimed to be the first homesteader in Nebraska.
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