Results 81 to 90 of about 975,233 (311)

Origin and the development of primates comparative cytogenetics

open access: yesJournal of Biological Research, 2002
Genetic and cytogenetic comparison in between man and non-human primates has largely contributed to the knowledge of the evolution of the Order Primates and in particular of man.
Luca Sineo
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Laser Beak Man: Sound Design

open access: yes, 2017
The Laser Beak Man: Sound Design investigates the two-dimensional visual world of Australian artist Tim Sharp who has autism, through its trans-dimensional expansion into the puppet based immersive theatre performance, Laser Beak Man.
Brumpton, Anthony
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Writing The see-through man: poetry and commentary

open access: yes, 2011
'Writing The See-Through Man: Poetry and Commentary' is a Creative Writing thesis in two parts. The first part is a collection of poems called The See-Through Man, written specifically for this project.
Goodson, RP
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

[Man and women assisting customer at drive-up window]

open access: yes, 1958
Man and women assisting customer at drive-up window at bank.
Douglass, Neal
core  

Russian man through the eyes of the first realist writers

open access: yesФилологический класс, 2005
The article is devoted to the study of the view on human nature, which was characteristic of the pioneers of the realistic direction of Russian literature.
doaj  

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