Results 31 to 40 of about 2,341,849 (265)

Aboriginal Maple Syrup Values Report [PDF]

open access: yes, 2014
This report examines the values associated with maple syrup practices in Aboriginal contexts. It is based on fifteen interviews conducted with Aboriginal people who have knowledge of maple syrup practices in Ontario.
Chrétien, Annette
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The urban environment : agendas and problems [PDF]

open access: yes, 2007
The United Nations estimate that by 2025 there will be around 5 billion people living in urban areas, more than the total world population 20 years ago.
Grierson, D.
core   +1 more source

Fever in our First Nations [PDF]

open access: yesCanadian Medical Association Journal, 2015
In a CMAJ practice article, Bagnall and colleagues describe acute rheumatic fever in a member of Canada’s immigrant population.[1][1] The same article correctly identifies Canada’s First Nations as a population at risk for this disease. Social determinants of health are contributory: poverty,
Janet, Gordon   +7 more
openaire   +2 more sources

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

People First, Nations Second: A New Role for the United Nations [PDF]

open access: yes, 2006
The tragedy of East Timor coming so soon after that of Kosovo has focused attention again on the weaknesses of previous United Nations missions that have been ad hoc, reactive, and narrowly focused on solving the international emergency of the moment ...
Maogoto, Jackson N
core   +1 more source

A Sure Thing? Online Gaming and Canada [PDF]

open access: yes, 2013
The legal status of gaming activities on First Nations land within Canada is complicated. The foci of this paper are two-fold. First, we trace the origin and expansion of First Nations gaming. Second, we analyze the potential of First Nations as hubs for
Holden, John T., Rodenberg, Ryan M.
core   +2 more sources

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