Results 41 to 50 of about 371,996 (314)

Perceptions of provider awareness of traditional and cultural treatments among Indigenous people who use unregulated drugs in Vancouver, Canada

open access: yesBMC Health Services Research
Introduction Indigenous people who use unregulated drugs (IPWUD) face significant barriers to care, including sparse availability of culturally safe health services.
Alexa Norton   +6 more
doaj   +1 more source

Fighting for the Taste Buds of Our Children

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2019
In this commentary, I focus on the impacts of Indian boarding school food on American Indian foodways and community as a source of acculturation that has a lasting effects even in the present day.
A-dae Romero-Briones
doaj   +1 more source

Our Children, Our Future: The Health and Well-being of First Nations Children in Manitoba, Canada.

open access: yesInternational Journal of Population Data Science, 2022
Objectives Given the impact of colonization and responding to Canada’s Truth and Reconciliation Commission, we aimed to provide baseline measures of First Nations children’s health and social outcomes in Manitoba, Canada.
Mariette Chartier   +8 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Creation of First Nations Health Profiles Through Data Linkage in Manitoba

open access: yesInternational Journal of Population Data Science, 2020
Background First Nation peoples (FNs) were not able to identify themselves within administrative datasets due to lack of FNs identifiers, which perpetuates a pan-indigenous approach in advocacy and evaluation capabilities.
Shravan Ramayanam
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Institutional Change On First Nations: Examining Factors Influencing First Nations’ Adoption of the Framework Agreement on First Nation Land Management

open access: yesJournal of Aboriginal Economic Development, 2013
In 1999 the Canadian Federal government passed the First Nations Land Management Act, ratifying the Framework Agreement on First Nation Land Management signed by the government and 14 original signatory First Nations in 1996. This Agreement allows First Nations to opt out of the 34 land code provisions of the Indian Act and develop individual land ...
Doidge, Mary   +2 more
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Our first First Nations physician [PDF]

open access: yesCanadian Medical Association Journal, 2014
Bridging Two Peoples: Chief Peter E. Jones, 1843–1909. Allan Sherwin. Wilfrid Laurier University Press; 2012. Peter Edmund Jones graduated in 1866 as a physician from Queen’s University in Kingston, Ontario. He was the first status Native Canadian to graduate from a Canadian medical school.
openaire   +1 more source

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