Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The "Queen of Europe" at the UN : why Angela Merkel should abandon Germany's bid for a permanent seat at the UN Security Council [PDF]
When Angela Merkel arrives at the United Nations for the opening of the 62nd session of the General Assembly on Tuesday [25 September] to deliver her first address as German chancellor she will be very well received. Just after two years in power she has
Hellmann, Gunther
core
Epidemiology of diabetes mellitus among First Nations and non-First Nations adults [PDF]
First Nations people in Canada experience a disproportionate burden of type 2 diabetes mellitus. To increase our understanding of this evolving epidemic, we compared the epidemiology of diabetes between First Nations and non-First Nations adults in Saskatchewan from 1980 to 2005.We used administrative databases to perform a population-based study of ...
Roland, Dyck +4 more
openaire +2 more sources
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
[Review of] Patsy West. The Enduring Seminoles: From Alligator Wrestling to Ecotourism [PDF]
Patsy West, long the archivist of photographs for the Seminole and Miccosukee Native nations of Florida, has written an exceptional book in her first full-length work, The Enduring Seminoles: From Alligator Wrestling to Ecotourism.
Kasee, Cynthia R.
core +1 more source
The Role of the Bible in the Formation of Philosophical Thought in Kievan Rus’ (as Exemplified by Ilarion of Kiev, Kliment Smolatič, and Kirill of Turov) [PDF]
The article is an attempt to critically evaluate the manifestations of the philosophical culture sprouting in Rus’. With the baptism in the Byzantine Rite, Rus’ in the 10th century joined the family of Christian nations and defined the future direction ...
Kroczak, Justyna
core +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source

