Results 61 to 70 of about 2,340,201 (311)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Nonalcoholic Fatty Liver Disease in Canadian First Nations and Non-First Nations Patients

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2016
Background. Features of nonalcoholic fatty liver disease (NAFLD) have yet to be described in the Canadian First Nations (FN) population. The aim of this study was to compare the prevalence, severity, and outcome of NAFLD in FN versus non-FN patients at ...
Julia Uhanova   +3 more
doaj   +1 more source

Traditional vs. Tagaq: Exploring the First Nations Relations in Canada Through Punk Inuk Throat Singer, Tanya Tagaq [PDF]

open access: yes, 2019
This research essay will be situated within the throat singing traditions of the Inuit First Nations people of Canada. As both Paula Conlon’s entry in the Grove Music Refernce and Elaine Keillor’s book describe, Inuit throat singing began as a tradition ...
Haines, Bridget S.
core   +1 more source

A report on the First Conference on Physiological and Physical Employment Standards, Canberra, Australia November 27 to 28, 2012 [PDF]

open access: yes, 2013
This is a report of the First Conference on Physiological and Physical Employment Standards. This was the first conference of its kind, attended by scientists, physicians, occupational medics, high-ranking politicians and military personal from ten ...
Milligan, Gemma, Tipton, Mike
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The Atlantic First Nations Water Authority: an Indigenous water utility guided by Etuaptmumk or Two-Eyed Seeing

open access: yesFACETS
The Atlantic First Nations Water Authority (AFNWA) is the first Indigenous-owned and operated water and wastewater utility in Canada, providing service to 12 First Nations (at the time of this publication), with a Board of Directors composed of Chiefs ...
Megan Fuller   +9 more
doaj   +1 more source

Supporting Self-Determined Indigenous Innovations: Rethinking the Digital Divide in Canada

open access: yesTechnology Innovation Management Review, 2018
This article seeks to revisit dominant narratives of digital technological development in Indigenous communities in Canada. By prioritizing Indigenous voices and drawing from concepts of self-determination and sovereignty, this analysis reorients ...
Jasmin Winter, Justine Boudreau
doaj   +1 more source

Time to change the focus of the conversation between First Nations and mining companies, from a positional based approach to an interest based approach [PDF]

open access: yes, 2013
Due to the growing interest of resource extraction in Northern British Columbia, specifically in the mining industry, Canada is poised to benefit with an increase in mineral exports while leaving the First Nations people where the resources are being ...

core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Facilitators and barriers of lung cancer screening participation: umbrella and systematic review of the global evidence

open access: yesBMC Public Health
Introduction Lung cancer is the leading cancer worldwide, accounting for 2.5 million new cases and 1.8 million deaths in 2022. Early identification of lung cancer through low-dose computed tomography screening is associated with improved outcomes ...
Sewunet Admasu Belachew   +3 more
doaj   +1 more source

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