Results 71 to 80 of about 29,704,411 (285)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Stochastic structural analysis of engineering components using the finite element method [PDF]

open access: yes, 1993
Bibliography: p. 113-123.This thesis investigates probabilistic and stochastic methods for structural analysis which can be integrated into existing, commercially available finite element programs.
Weber, Marc Anton
core   +1 more source

Certificate of Incorporation of the Order of the First Families of Virginia, 1607-1620

open access: yes, 1913
Includes a copy of the certificate of incorporation of the Order of the First Families of Virginia dated May 7, 1913. Also contains signed statement by George M.
Order of the First Families of Virginia, 1607-1620
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

ASSESSMENT THE PROBABILITY OF FAILURE OF A REINFORCED CONCRETE FRAME UNDER A COLUMN REMOVAL SCENARIO USING THE FIRST-ORDER RELIABILITY METHOD

open access: yesInternational Journal for Computational Civil and Structural Engineering
The article considers issues related to the assessment of survivability of structural reinforced concrete systems in special limit states under the scenario of removal of one of the load-bearing columns within the framework of the probabilistic approach.
Ngoc Tuyen Vu   +2 more
doaj   +1 more source

Reliability-based multiobjective optimization using the satisficing trade-off method

open access: yesMechanical Engineering Journal, 2014
This study proposes a reliability-based multiobjective optimization (RBMO) approach using the satisficing trade-off method (STOM). STOM is a multiobjective optimization method that obtains a highly accurate single Pareto solution, regardless of the shape
Nozomu KOGISO   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Development of simple estimation method for the influence of parameter uncertainty of probability distributions against evaluation result of probabilistic fracture mechanics

open access: yesNihon Kikai Gakkai ronbunshu, 2016
Probabilistic fracture mechanics (PFM) analysis is an evaluation method for the structural integrity of components containing a crack, with considering the random variability of the input physical parameters, such as crack growth rate.
Satoshi OKAJIMA   +2 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

First-Order Saddlepoint Approximation for Reliability Analysis

open access: yes, 2004
In the approximation methods of reliability analysis, nonnormal random variables are transformed into equivalent standard normal random variables. This transformation tends to increase the nonlinearity of a limit-state function and, hence, results in ...
Sudjianto, Agus, Du, Xiaoping
core   +1 more source

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